If you’re interested in starting medication for depression, you and your healthcare provider will need to work together to find the right fit for you.
In some cases, you may need to try more than one medication before you find the right one, according to Jacques Ambrose, MD, MPH, FAPA, Psychiatrist at Columbia University Irving Medical Center.
Jacques Ambrose, MD, MPH, FAPA, is a Psychiatrist at Columbia University Irving Medical Center.
References
MedlinePlus. (2025). Antidepressants.
National Institutes of Health. (2022). Talking with your doctor or health care provider.
National Institute of Mental Health. (2023). Mental health medications.
Scheffler, Z. M. et al. (2023). Antidepressants. StatPearls.
Why trust our experts?

Written by:
Lauren Smith, MALauren Smith, MA, has worked in health journalism since 2017. Before joining GoodRx, she was the senior health editor and writer for HealthiNation.

Reviewed by:
Mera Goodman, MD, FAAPMera Goodman, MD, FAAP, is a board-certified pediatrician. Prior to practicing medicine, she worked as a management consultant.
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