Medications for acetaminophen overdose are used to treat acetaminophen toxicity. These medications also have other uses, such as treating certain liver conditions, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. They work for acetaminophen overdose by replenishing glutathione levels in the liver, which helps to detoxify harmful substances and protect the liver from damage. The main class of medication used is mucolytics. Acetylcysteine (Acetadote) is a common example and is available in an injectable form.