Acetylcysteine (Acetadote) is an antidote that's used during an acetaminophen overdose to prevent or lessen serious injury to the liver. It's given in a healthcare setting (e.g., urgent care, emergency room) by a healthcare provider. The medication is available as an intravenous (IV) infusion and a generic oral solution that can be given by mouth or through a feeding tube. The most common side effects of the injection version include redness and flushing of the skin, while nausea and vomiting are more common with the oral version.
Lessen liver injury from acetaminophen overdose
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Cumberland Pharmaceuticals Inc. (2023). Acetadote- acetylcysteine injection, solution [package insert]. DailyMed.
Fresenius Kabi USA, LLC. (2022). Acetylcysteine solution [package insert]. DailyMed.
MedlinePlus. (2023). Acetaminophen overdose.
National Cancer Institute. (n.d.). Glutathione.
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