Mucolytics are used to treat chronic obstructive pulmonary disease (COPD), cystic fibrosis, and bronchitis. They also have other uses, such as helping to clear mucus in conditions like pneumonia. Mucolytics work by breaking down the mucus in your airways, making it easier to cough up and clear from your lungs. These medications come in different forms, including oral solutions and inhalations. Examples include acetylcysteine (Acetadote) and dornase alfa (Pulmozyme). You can choose the form that best fits your needs.