Key takeaways
Alprazolam (Xanax) and chlordiazepoxide (Librium) are both benzodiazepines used to treat anxiety, but they have some key differences. Alprazolam is also approved for treating panic disorder, while chlordiazepoxide is used for alcohol withdrawal and preoperative anxiety. Alprazolam works quickly, often within 30 minutes, and is typically taken three times a day. In contrast, chlordiazepoxide takes longer to kick in, up to 4 hours, and can be taken up to four times a day depending on the condition being treated. Alprazolam is available in various forms, including immediate- release tablets, quick-dissolving tablets, and liquid. Chlordiazepoxide is only available as a capsule. Both medications carry risks of addiction, dependence, and withdrawal. Chlordiazepoxide is noted for its longer-lasting presence in the body, which can lead to prolonged side effects. Additionally, both medications should be avoided during pregnancy due to potential harm to the baby.
