Skip to main content

Compare
Xanax vs. Buspar

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Alprazolam (Xanax) and buspirone (Buspar) are both used to treat anxiety, but they have some key differences. Alprazolam is a benzodiazepine that works quickly, often within 30 minutes, and is typically taken three times a day. It is a controlled substance with a risk of dependence and withdrawal symptoms. Common side effects include drowsiness and memory problems. In contrast, buspirone is not a controlled substance and has a much lower risk of dependence. It takes longer to start working, usually a few weeks, and is taken twice daily. Buspirone's common side effects include dizziness and drowsiness. Unlike alprazolam, buspirone is not effective for immediate relief of anxiety or panic attacks. Additionally, buspirone can be taken by children as young as six years old. Both medications are available as lower-cost generics.

Alprazolam

(Xanax)

Get free coupons

Buspirone

 

Get free coupons

Summary for Xanax

Prescription only

Alprazolam (Xanax) is a benzodiazepine. It's approved to treat generalized anxiety disorder (GAD) and panic attacks in adults. It's taken by mouth, typically 3 times a day or as directed by your healthcare team. To avoid the risk of dependence, alprazolam (Xanax) is meant for short-term treatment only. Some of the more common side effects of this medication include drowsiness and memory problems. You should avoid drinking alcohol while taking alprazolam (Xanax) because this can lead to serious interactions.

Indications for Xanax

Pros and Cons for Xanax

Pros

  • Taken by mouth
  • Can start to work in 30 minutes
  • Available as quick-dissolving tablets or liquid for people who have trouble swallowing pills

Cons

Common Side Effects for Xanax

Generalized anxiety disorder:

  • Drowsiness (41%)
  • Lightheadedness (21%)
  • Dry mouth (15%)

Panic disorder:

  • Drowsiness (77%)
  • Fatigue (49%)
  • Poor coordination (40%)
  • Memory issues (33%)
  • Irritability (33%)
  • Appetite changes (28-33%)
  • Thinking problems (29%)
  • Constipation (26%)

Side effects listed are for the immediate-release forms. Side effects for extended-release form might differ.

Warnings for Xanax

  • Sedation and difficulty breathing
  • Potential for misuse, addiction, dependence, and withdrawal
  • Effect on driving and concentration
  • Harm to babies
  • Interactions with other medications
  • Use with caution in people with depression

Summary for Buspar

Prescription only

Buspirone tablets help manage and relieve anxiety in adults. It belongs to a drug class called anxiolytics (or anti-anxiety medications). The tablets are taken by mouth, typically twice daily. Common side effects are dizziness, nausea, headache, and nervousness. Buspirone isn't a controlled substance. The brand name Buspar is no longer available, but you can get the generic buspirone tablets.

Indications for Buspar

Pros and Cons for Buspar

Pros

Cons

Common Side Effects for Buspar

  • Dizziness (12%)
  • Drowsiness (10%)
  • Nausea (8%)
  • Headache (6%)
  • Nervousness (5%)

Warnings for Buspar

  • Serotonin syndrome
  • Effect on driving and concentration
  • Not safe with monoamine oxidase inhibitors (MAOIs)
  • Doesn't help relieve withdrawal symptoms from other anxiety medications

Prices with our coupons for Xanax vs. Buspar

Price Card Drug Icon
Alprazolam30 tablets / 0.5mg
$8.65$18.20
Get free coupons
More Information
Price Card Drug Icon
Buspirone60 tablets / 10mg
$4.00$4.00
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.