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Compare Vyvgart vs. Vyvgart Hytrulo

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Vyvgart (efgartigimod alfa)
    Vyvgart hytrulo
  • Vyvgart (efgartigimod alfa)
    Vyvgart hytrulo

  • Summary of Vyvgart vs. Vyvgart Hytrulo

    Summary for Neonatal Fc receptor blocker
    Prescription only

    Vyvgart (efgartigimod alfa or efgartigimod alfa-fcab) is an FDA-approved IV injection that's used to treat certain adults with generalized myasthenia gravis (gMG). It belongs to a drug class called neonatal Fc receptor blockers, which work by lowering harmful antibodies that interferes with communication between your nerves and muscles. The medication is given IV, typically at an infusion center, your prescriber's office, or at home. Common side effects include respiratory tract infections, headache, and urinary tract infection (UTIs).

    Summary for Neonatal Fc receptor blocker / Endoglycosidase
    Prescription only

    Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) is an injection used to treat certain adults with generalized myasthenia gravis (gMG). It's also FDA approved as a treatment for chronic inflammatory demyelinating polyneuropathy (CIDP). The medication comes in a vial or prefilled syringe, and it's injected under your skin. Common side effects include injection site reactions and headache.

  • Indications of Vyvgart vs. Vyvgart Hytrulo

    Indications for
    •Generalized myasthenia gravis (gMG) in adults with anti-AChR antibodies
    Indications for
    •Generalized myasthenia gravis (gMG) in adults with anti-AChR antibodies
    •Chronic inflammatory demyelinating polyneuropathy (CIDP)

  • Pros and Cons of Vyvgart vs. Vyvgart Hytrulo

    Pros and Const for Neonatal Fc receptor blocker
    Pros
    •Starts to work within 1 to 2 weeks
    •Only injected once a week per treatment cycle
    •Treatment cycles can lasts several weeks
    Cons
    •Must be given by IV infusion
    •Can raise the risk of infections
    •Only approved for people with gMG who have anti-AChR antibodies
    Pros and Const for Neonatal Fc receptor blocker / Endoglycosidase
    Pros
    •Can be injected at home
    •Injected under the skin
    •FDA approved for both gMG and CIDP
    Cons
    •Commonly causes injection site reactions
    •Can raise the risk of infections
    •Only approved for people with gMG who have anti-AChR antibodies

  • Common Side Effects of Vyvgart vs. Vyvgart Hytrulo

    Common Side Effects for
    •Respiratory tract infection (33%)
    •Headache (32%)
    •Urinary tract infection (10%)
    Common Side Effects for

    gMG

    •Injection site reactions (38%)
    •Headache (at least 10%)

    CIDP

    •Injection site reactions (15%)

  • Warnings of Vyvgart vs. Vyvgart Hytrulo

    Common Side Effects for
    •Infections
    •Allergic reactions
    •Infusion-related reactions
    Common Side Effects for
    •Infections
    •Allergic reactions
    •Injection-related reactions

  • Prices with our coupons for Vyvgart vs. Vyvgart Hytrulo

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