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Tolnaftate vs. Clotrimazole

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Tolnaftate

 

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Clotrimazole

(Lotrimin)

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Summary for Tolnaftate

Over-the-counter

Tolnaftate is an over-the-counter (OTC) antifungal medication that's applied to the skin to treat ringworm, jock itch, and athlete's foot. It also helps relieve symptoms like itching, burning, cracking, and redness from these fungal infections. This medication comes in different topical forms, including a spray, powder spray, cream, and liquid. Tolnaftate can be used for adults and children 2 years and older, unless otherwise directed by a provider. Most people have few to no side effects while using this medication, though some can have mild skin irritation.

Indications for Tolnaftate

Pros and Cons for Tolnaftate

Pros

  • Available as a generic, over-the-counter medication
  • Available in different topical formulations, such as powder spray, liquid, and cream
  • Typically minor or mild side effects

Cons

  • Can take up to a month to treat athlete's foot or ringworm
  • Only works on some fungal infections; doesn't work on fungal infections of the scalp or nails
  • Can't use on children under 2 years old, unless a provider says it's okay

Common Side Effects for Tolnaftate

Warnings for Tolnaftate

  • Use only on your skin
  • Flammable and possible bursting (topical sprays only)

Summary for Clotrimazole

Prescription or over-the-counter

Clotrimazole (Lotrimin) is an antifungal medication used to treat certain skin fungal infections. A healthcare professional might also prescribe it for diaper rash. It's available over the counter (OTC) and by prescription as a cream or topical solution that you apply to your skin. You usually use it two times a day for a few weeks, depending on the infection. The most common side effect is skin irritation.

Indications for Clotrimazole

Pros and Cons for Clotrimazole

Pros

  • Applied directly to the affected area(s)
  • Can treat multiple fungal skin infections
  • Safe for both adults and children

Cons

  • Need to apply twice daily
  • Must use every day for several weeks
  • Can cause mild skin irritation

Common Side Effects for Clotrimazole

  • Skin irritations (e.g., itching, redness)

Warnings for Clotrimazole

  • Use only on your skin

Prices with our coupons for Tolnaftate vs. Clotrimazole

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Tinactin1 bottle / 133g of 1%
$10.06-
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Clotrimazole1 tube / 30g of 1%
$13.97$38.98
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