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Tobradex vs. Floxin Otic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

TobraDex (tobramycin/dexamethasone) and Floxin Otic (ofloxacin) are both prescription medications, but they treat different types of infections. TobraDex is a combination of an aminoglycoside antibiotic and a corticosteroid, used as eye drops or ointment to treat bacterial eye infections and reduce inflammation. In contrast, Floxin Otic is a fluoroquinolone antibiotic used as ear drops to treat various ear infections, such as swimmer's ear and middle ear infections. TobraDex combines two medications for convenience, while Floxin Otic contains only an antibiotic. TobraDex can cause side effects like eye irritation and increased eye pressure if used for more than 10 days, whereas Floxin Otic may cause ear discomfort and, rarely, dizziness. Additionally, TobraDex is not suitable for viral or fungal eye infections, and Floxin Otic should not be used in the eyes. Both medications are available in generic forms, making them more affordable.

TobraDex

(tobramycin / dexamethasone)

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ofloxacin ear drops

 

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Summary for Tobradex

Prescription only

TobraDex (tobramycin / dexamethasone) is available as eye drops and an eye ointment. It's used to treat and relieve bacterial eye infections. This medication contains tobramycin (an aminoglycoside antibiotic that helps fight the infection) and dexamethasone (a corticosteroid that helps lower eye inflammation). Most people have few to no side effects from the medication when they use it as directed. But the medication can raise your eye pressure if you use it for more than 10 days.

Indications for Tobradex

  • Eye inflammation from a bacterial infection in the eye
  • Eye inflammation when there's a risk for a bacterial infection in the eye

Pros and Cons for Tobradex

Pros

  • Relieves eye inflammation and treats bacterial eye infection at the same time
  • Combines two medications into one eye product for convenience
  • Applied directly where the infection is (in the eye)
  • Is safe and work wells for children as young as 2 years old
  • Eye drops are available as a lower-cost generic

Cons

  • Need to use multiple times a day
  • Must shake the eye drop bottle before each use, which can be easy to forget
  • Can cause eye irritation or allergic reactions for some people
  • Requires an eye exam after 10 days of use to check your eye pressure
  • Only treats some bacterial eye infections; it doesn't treat fungal or viral infections

Common Side Effects for Tobradex

  • Eye irritation
  • Eye redness
  • Itchy eyelids
  • Swollen eyelids

Warnings for Tobradex

  • Only use on the surface of the eye
  • Higher eye pressure
  • New or worsened eye infections
  • New eye problems (e.g., injury, cataracts)
  • Possible allergic reaction

Summary for Floxin Otic

Prescription only

Ofloxacin is a prescription otic medication, or ear drop. It's a fluoroquinolone antibiotic that's used to treat different types of ear infections, such as swimmer's ear and middle ear infection, in adults and children. This medication is given as 5 or 10 drops into the infected ear once or twice a day for 7 or 14 days, depending on your age and the type of ear infection you have. The most common side effect is ear discomfort from applying the drops.

Indications for Floxin Otic

Pros and Cons for Floxin Otic

Pros

  • Works well to treat certain types of ear infections
  • Can safely use in babies for certain ear infections
  • Available as a lower-cost generic

Cons

  • Doesn't contain medication to help with ear pain
  • Must lie still for 5 minutes after placing the drops into the ear to make sure the medication is absorbed
  • Must warm up the medication in your hands before putting the drops into the ear to prevent dizziness

Common Side Effects for Floxin Otic

  • Pain or irritation where the medication touches the ear (up to 17%)
  • Itching (up to 4%)

Warnings for Floxin Otic

  • Use only in the ear
  • Severe allergic reactions
  • Risk of developing new infection

Prices with our coupons for Tobradex vs. Floxin Otic

Price Card Drug Icon
Tobramycin/Dexamethasone1 eye dropper / 5ml of 0.3%/0.1%
$28.07$50.26
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Price Card Drug Icon
Ofloxacin1 ear dropper / 5ml of 0.3%
$19.60$154.49
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