Pimozide
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Adderall
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Summary for Pimozide
Pimozide is an oral antipsychotic medication used for Tourette syndrome after other standard treatments haven't worked. It's thought to work by lowering dopamine levels in the brain, which helps to reduce tics. Generally, adults take more than one dose per day, while children 12 years and older usually take one dose at bedtime. Side effects include sleepiness, drowsiness, and difficulty moving muscles. Although the brand medication Orap is no longer available, the generic version still is.
Indications for Pimozide
- Treatment of Tourette syndrome after other standard medications haven't worked
Pros and Cons for Pimozide
Pros
- One of the few medications that's FDA approved to treat Tourette syndrome
- Can be used in children 12 years and older
- Available as a lower-cost generic
Cons
- Generally not a first-choice treatment option
- Not a good option for people with certain heart conditions
- Interacts with a lot of medications
Common Side Effects for Pimozide
Adults:
- Sleepiness (14%)
- Inability to move muscles on your own (8%)
- Restlessness (8%)
- Drowsiness (7%)
- Dry mouth (5%)
- Behavior problems (5%)
Children:
- Sleepiness (28%)
- Behavior problems (28%)
- Weakness (25%)
- Headache (22%)
- Drooling (14%)
Warnings for Pimozide
- Movement problems
- Neuroleptic malignant syndrome
- Higher risk of infection
- Heart rhythm changes
Summary for Adderall
Adderall is a stimulant medication that's used to treat attention deficit-hyperactivity disorder (ADHD) and narcolepsy in adults and children. It contains the instant-release (IR) forms of dextroamphetamine and amphetamine salts. Adderall is available as a brand-name and lower-cost generic tablet that's taken by mouth. Your psychiatrist will adjust the dosage for you based on how well the medication works for you. Common side effects include trouble sleeping and loss of appetite.
Indications for Adderall
- Attention deficit-hyperactivity disorder (ADHD)
- Narcolepsy (daytime sleepiness)
Pros and Cons for Adderall
Pros
- First-choice option for ADHD in children and adults
- Starts working within an hour after taking
- Available as a lower-cost generic
- Can use together with behavioral counseling or other non-medication therapies to treat ADHD
Cons
- Has a risk of misuse and dependency
- A controlled medication, so there are special requirements for getting the prescription filled
- Dose needs to be raised and lowered slowly to avoid side effects and withdrawal symptoms
- Not available as a liquid or patch form (unlike methylphenidate (Ritalin))
Common Side Effects for Adderall
- Upset stomach
- Lower appetite
- Weight loss
- Nervousness
- Changes in mood
- Trouble sleeping
Warnings for Adderall
- Misuse and addiction
- Dependence and withdrawal
- Serious heart problems
- Aggressive behavior and psychosis
- Slowed growth in children
- Seizures
- Blood circulation problems (such as Raynaud's phenomenon)
- Serotonin syndrome
- Drug interactions
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