Pred Forte vs. Durezol for Eye Inflammation: Important Differences and Potential Risks.

Key takeaways

Prednisolone acetate (Pred Forte) and Durezol (difluprednate) are both corticosteroid eye drops used to treat inflammation, but they have some differences. Prednisolone acetate is used for eye injuries, swelling, and allergies, and used 2 to 4 times daily depending on the condition. In contrast, Durezol is used mainly for eye inflammation and pain after surgery, and is typically used 4 times a day for at least 2 weeks. Prednisolone acetate and Durezol can both cause eye irritation, but Durezol specifically slows down healing and can lead to higher eye pressure and cataracts with long-term use. Both medications are available as lower-cost generics.

prednisolone eye drops

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Difluprednate

(Durezol)

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Summary for Pred Forte

Prescription only

Prednisolone eye drops is a type of steroid eye drop. It helps treat eye inflammation in adults and children. The medication helps relieve symptoms like itchy eye, eye redness, and swelling in the eye. Prednisolone eye drops come as a generic as well as brand names like Pred Forte and Pred Mild. This eye drop is usually used in the affected eye(s) 2 to 4 times a day. Side effects can include temporary burning and stinging in the eye when you put the drops in.

Indications for Pred Forte

Eye inflammation

Pros and Cons for Pred Forte

Pros

Few side effects
Approved for both adults and children

Cons

Might have to use the eye drops up to 4 times a day
Some formulations contain sulfite, so not a good option for people with a sulfite allergy

Common Side Effects for Pred Forte

Temporary burning or stinging in the eye
Feeling like there's something in your eye

Warnings for Pred Forte

Risk of eye infection when used for a long time
Risk of eye problems when used for a long time
Slow healing of the eye after cataract surgery
Severe allergic reaction

Summary for Durezol

Prescription only

Difluprednate 0.05% eye drops, also known by its brand name Durezol, is a prescription corticosteroid that's used to treat eye inflammation. It's approved for adults and children who've just had eye surgery or who have anterior uveitis. The drops are placed directly in the eye(s) 4 times per day for at least 2 weeks. After this time, your prescriber will slowly lower your dose until it's safe to stop the medication altogether. Typical side effects include swelling in the front of the eye and light sensitivity. Difluprednate (Durezol) is available as a generic.