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Compare Pred Forte vs. Durezol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Prednisolone acetate (Pred Forte) and Durezol (difluprednate) are both corticosteroid eye drops used to treat inflammation, but they have some differences. Prednisolone acetate is used for eye injuries, swelling, and allergies, and used 2 to 4 times daily depending on the condition. In contrast, Durezol is used mainly for eye inflammation and pain after surgery, and is typically used 4 times a day for at least 2 weeks. Prednisolone acetate and Durezol can both cause eye irritation, but Durezol specifically slows down healing and can lead to higher eye pressure and cataracts with long-term use. Both medications are available as lower-cost generics.

  • Prednisolone (Pred Forte)
    Difluprednate (Durezol)
  • Prednisolone (Pred Forte)
    Difluprednate (Durezol)

  • Summary of Pred Forte vs. Durezol

    Summary for Corticosteroid
    Prescription only

    Prednisolone (Pred Forte) is a steroid used in the eye. It works well to control allergic reactions and inflammation (swelling) in the eye.

    Summary for Corticosteroid
    Prescription only

    Difluprednate 0.05% eye drops, also known by its brand name Durezol, is a prescription corticosteroid that's used to treat eye inflammation. It's approved for adults and children who've just had eye surgery or who have anterior uveitis. The drops are placed directly in the eye(s) 4 times per day for at least 2 weeks. After this time, your prescriber will slowly lower your dose until it's safe to stop the medication altogether. Typical side effects include swelling in the front of the eye and light sensitivity. Difluprednate (Durezol) is available as a generic.

  • Indications of Pred Forte vs. Durezol

    Indications for
    •Eye injury
    •Swelling or allergies in the eye
    Indications for
    •Eye inflammation and pain from eye surgery
    •Endogenous anterior uveitis

  • Pros and Cons of Pred Forte vs. Durezol

    Pros and Const for Corticosteroid
    Pros
    •Works in the eye to relieve symptoms without having the side effects of oral steroids
    •Works quickly to relieve symptoms
    •Available in generic form
    Cons
    •Depending on the condition, you might have to use the eye drops up to 4 times a day
    •Long-term use will require your healthcare provider to monitor your eyes more regularly.
    •Contains sulfite, which is not good for those with allergies to sulfite
    Pros and Const for Corticosteroid
    Pros
    •Works well to lessen eye inflammation and eye pain
    •Few side effects since the medication is placed directly into the eyes
    •Approved for people of all ages
    Cons
    •Need to use four times a day
    •Can't use if you have an eye infection
    •Might be difficult for some people to use correctly

  • Common Side Effects of Pred Forte vs. Durezol

    Common Side Effects for
    •Burning, stinging
    •Feeling like there's something in your eye
    •Changes in taste
    Common Side Effects for
    •Eye swelling (up to 15%)
    •Eye redness (up to 15%)
    •Eye pain (up to 15%)
    •Eye sensitivity to light (up to 15%)

  • Warnings of Pred Forte vs. Durezol

    Common Side Effects for
    •Eye Problems
    •Severe Allergic Reactions
    Common Side Effects for
    •For use in the eye only
    •Possible eye infections and eye problems when used for a long time
    •Slow healing of the eye after an eye procedure
    •Damage to contact lenses

  • Prices with our coupons for Pred Forte vs. Durezol

    Learn more about Prednisolone
    Learn more about Difluprednate

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