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Compare Metronidazole vs. Miconazole

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Metronidazole (Flagyl)
    Miconazole (Monistat)
  • Metronidazole (Flagyl)
    Miconazole (Monistat)

  • Summary of Metronidazole vs. Miconazole

    Summary for Nitroimidazole antibiotic
    Prescription only

    Metronidazole (Flagyl) is an oral antibiotic for adults and children. It's used to treat certain bacterial and parasitic infections, including bacterial vaginosis (a type of vaginal bacteria infection) and trichomoniasis (a sexually transmitted infection, or STI). Metronidazole (Flagyl) is taken by mouth, typically 3 times a day. Some common side effects of this medication include diarrhea, nausea, and vomiting. Avoid drinking alcohol while taking and for 3 days after stopping metronidazole (Flagyl) because this combination can cause a serious reaction. Metronidazole (Flagyl) is available as a lower-cost generic.

    Summary for Antifungal

    Miconazole (Monistat) is used to treat a vaginal yeast infection in adults and children 12 years and older. It's available over the counter as vaginal creams, inserts/suppositories, or combination kits. The entire treatment lasts 1, 3, or 7 days, depending on the product. Common side effects include mild vaginal burning, irritation, and itching.

  • Indications of Metronidazole vs. Miconazole

    Indications for

    Treatment of certain bacterial and parasitic infections, including:

    •Trichomoniasis
    •Amebiasis (parasitic gut infection)
    •Serious bacterial infections, such as:
    •Abdominal infection (including peritonitis)
    •Skin infections
    •Gynecological infections (including endometritis)
    •Bloodstream infection (septicemia)
    •Bone and joint infections
    •Central nervous system infections (meningitis)
    •Lung infections (lower respiratory tract infections)
    •Heart infection (endocarditis)
    Indications for
    •Vaginal yeast infections
    •Itching and irritation caused by a vaginal yeast infection

  • Pros and Cons of Metronidazole vs. Miconazole

    Pros and Const for Nitroimidazole antibiotic
    Pros
    •Taken by mouth
    •Available as a lower-cost generic medication
    •Can be used to treat different types of bacterial infection
    •Immediate-release formulations can be taken with or without food
    Cons
    •Immediate-release formulations needs to be taken multiple times a day for most infections
    •Serious interaction with alcohol
    •Can cause metallic taste in mouth
    •Not recommended while breastfeeding
    Pros and Const for Antifungal
    Pros
    •Available over the counter
    •Many treatment options (1, 3, or 7 days)
    •Targets infection directly at the site
    Cons
    •Can cause vaginal burning, itching, or irritation
    •Might be messy or cause leakage
    •Requires vaginal insertion

  • Common Side Effects of Metronidazole vs. Miconazole

    Common Side Effects for

    Please note: These are common side effects reported by people who took extended-release metronidazole (Flagyl)

    •Headache (18%)
    •Inflammation of the vagina (15%)
    •Nausea (10%)
    •Metallic taste (9%)
    •Flu-like symptoms (6%)
    Common Side Effects for
    •Vaginal burning
    •Vaginal irritation
    •Vaginal itching

  • Warnings of Metronidazole vs. Miconazole

    Common Side Effects for
    •Possible risk of cancer
    •Serious allergic reactions
    •Brain and nerve problems
    •Liver and kidney problems
    •Risk of fungal infection
    •Risk of drug resistance
    •Lower white blood cell counts
    •Interaction with other medications
    Common Side Effects for
    •Damage to condoms and diaphragms
    •Symptoms don't go away

  • Prices with our coupons for Metronidazole vs. Miconazole

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    Learn more about Miconazole

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