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Loratadine vs. Cetirizine

Loratadine (Claritin) is an over-the-counter antihistamine for adults and kids. It helps relieve allergy symptoms like a runny nose, sneezing, and watery eyes. This allergy medication is taken by mouth, usually once a day. It comes as different formulations, including regular tablets, chewable tablets, and a liquid. Loratadine (Claritin) is a non-drowsy allergy medication because it's less likely to make you sleepy. Other side effects can include headache and feeling tired. Loratadine (Claritin) is available as a brand-name and generic.

• Short-term relief of allergy symptoms (runny nose, itchy nose or throat, itchy or watery eyes)

• Headache (12%)
• Sleepiness (8%)
• Feeling tired (4%)
• Dry mouth (3%)

• Sleepiness
• Accidentally taking too much medication
• Caution use in people with phenylketonuria (PKU) - chewable tablets and orally disintegrating tablets

Cetirizine (Zyrtec) is an antihistamine. It's used for relief of allergy symptoms, such as runny nose or watery eyes, in adults and children. Cetirizine (Zyrtec) is also a safe option for people who are pregnant. This medication is available in different formulations, including tablets and liquid solutions. Typically, cetirizine (Zyrtec) is taken by mouth once per day. The most common side effect of cetirizine (Zyrtec) is sleepiness. But it's less likely to make you drowsy compared to some other antihistamines, such as diphenhydramine (Benadryl).

• Short-term relief of allergy symptoms (sneezing, runny nose, itchy or watery eyes, itching of the nose or throat)
• Relief of itchiness due to chronic (long-term) hives in children ages 6 months to under 6 years old - certain liquid solutions only

People 12 years of age and older:

• Sleepiness (14%)
• Tiredness (6%)
• Dry mouth (5%)

Children age 6 to under 12 years:

• Headache (11-14%)
• Sore throat (3-6%)
• Stomach pain (4-6%)
• Cough (3-4%)
• Sleepiness (2-4%)

• Sleepiness
• Accidentally taking too much medication