Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Vardenafil (former brand names: Levitra, Staxyn) and sildenafil (Viagra) are both medications used to treat erectile dysfunction (ED), but they have some differences. Vardenafil is available as a generic and comes in tablet and orally disintegrating tablet (ODT) forms, while sildenafil is available as a generic and brand Viagra but only in tablet form. You typically take vardenafil about an hour before sexual activity, and it can start working in as little as 15 minutes, whereas sildenafil is taken 30 minutes to 4 hours before sex. Both medications should not be taken more than once a day. Common side effects for both include headaches and flushing, but sildenafil has a higher incidence of these side effects. Additionally, vardenafil might work slightly faster than sildenafil and is available in a form that dissolves on your tongue, which can be helpful if you have trouble swallowing pills. Both medications require a prescription and cannot be taken if you have had a recent heart attack or stroke or if you are taking nitrates for chest pain.
Vardenafil
Sildenafil (Viagra)
Vardenafil
Sildenafil (Viagra)
Summary of Levitra vs. Viagra
Summary for PDE-5 inhibitor
Prescription only
Vardenafil is a first-choice medication for erectile dysfunction (ED). It's no longer sold under the brand name Levitra, but it's available as generic tablets and orally disintegrating tablets (ODTs). Common side effects of vardenafil include headache, flushing, and stuffy nose. Interactions between vardenafil and other medications generally involve those that lower blood pressure.
Summary for PDE-5 inhibitor
Prescription only
Sildenafil (Viagra) is a tablet that's taken by mouth for erectile dysfunction (ED) in adults. It works as a phosphodiesterase-5 (PDE-5) inhibitor to help people get an erection or keep an erection that lasts for sex. You only take a dosage when you need it (usually about an hour, or anywhere from 30 minutes to 4 hours, before sex). Take sildenafil (Viagra) no more than once a day. Otherwise, it can put you at risk of serious side effects, such as vision loss or low blood pressure. Other more common side effects include headache and flushing. Sildenafil (Viagra) is a brand-name and generic medication.