Gammagard S/D
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Gammagard Liquid
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Summary for Gammagard S/D
Gammagard S/D is an immunoglobulin (also known as an antibody). Gammagard S/D is used for treating adults and children who have certain immune system problems, such as immunoglobulin G deficiency (a type of primary immunodeficiency). This medication raises the amount of immunoglobulin G (IgG) in the body to help the immune system work as it should and to prevent complications from certain health problems. Gammagard S/D is given as an infusion through the veins. Side effects include headache, chills, and back pain.
Indications for Gammagard S/D
Medical conditions that happen when your immune system is missing components or not working like it should:
- Primary immunodeficiency (PI) in adults and children ages 2 years and older
- Prevention of bacterial infections from a blood and bone marrow cancer called chronic lymphocytic leukemia (CLL)
- Prevention and treatment of bleeding from low platelets (idiopathic thrombocytopenic purpura or ITP)
- Prevention of widening of coronary arteries (aneurysm) in children with Kawasaki syndrome
Pros and Cons for Gammagard S/D
Pros
- Can help with many different immune problems
- Can be safely given to children with certain conditions
- Has low IgA content, which means less chance of severe allergic reactions in people with IgA deficiency
Cons
- Given as an IV infusion (an injection into the vein)
- Has a lot of potential risks, such as kidney and lung problems
- Available as a brand-name medication only
Common Side Effects for Gammagard S/D
- Headache (31%)
- Nausea (22%)
- Chills (19%)
- Fatigue (11%)
- Fever (11%)
- Back pain (8%)
- Stomach pain (8%)
- Diarrhea (8%)
Warnings for Gammagard S/D
- Kidney failure
- Blood clots
- Serious allergic reactions
- Swelling of the brain
- Anemia due to breakdown of red blood cells
- Lung problems
- Risk of too much sodium
- Infection
Summary for Gammagard Liquid
Gammagard Liquid is an immunoglobulin (antibody) infusion known as intravenous immunoglobulin (IVIG). It treats certain immune-related conditions, including primary immunodeficiency (PI), multifocal motor neuropathy (MMN), and chronic inflammatory demyelinating polyneuropathy (CIDP). Gammagard Liquid is typically infused through the vein, but can also be given as an infusion under the skin for PI. How often you receive a dose differs depending on your condition, but can range from weekly to every 4 weeks. Gammagard Liquid can raise your risk of serious side effects, including blood clots and kidney problems.
Indications for Gammagard Liquid
- Primary humoral immunodeficiency or PI in adults and children ages 2 years and older
- Multifocal motor neuropathy (MMN) in adults
- Chronic inflammatory demyelinating polyneuropathy (CIDP) in adults
Pros and Cons for Gammagard Liquid
Pros
- Can be given as IV or SQ infusion for PI
- Can be given at home, if your prescriber approves
- Conveniently stored at room temperature or in the refrigerator
Cons
- Infusion site reactions, like swelling or redness, are very common for under-the-skin injections.
- Has a lot of potential risks, such as kidney and lung problems
- Requires occasional blood tests to check for side effects and the need for dose adjustments
Common Side Effects for Gammagard Liquid
Primary humoral immunodeficiency (IV infusion):
- Headache (48%)
- Feeling tired (23%)
- Fever (28%)
- Nausea (18%)
- Diarrhea (15%)
- Vomiting (15%)
- Cough (13%)
- Chills (13%)
- Dizziness (13%)
- Pain in arms or legs (12%)
Multifocal motor neuropathy:
- Headache (32%)
Chronic inflammatory demyelinating polyneuropathy:
- Headache (40%)
- Fever (10%)
Warnings for Gammagard Liquid
- Risk of blood clots
- Kidney problems
- Serious allergic reactions
- Inflammation of the brain
- Anemia due to breakdown of red blood cells
- Spread of local infection
- Lung problems
- Risk of infection
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