Key takeaways
Buspar (buspirone) and Xanax (alprazolam) are FDA approved to treat anxiety. Xanax is also FDA approved to treat panic disorder. Buspar works by affecting serotonin levels. Xanax works by affecting a chemical GABA (gamma-aminobutyric acid). Buspar is typically taken twice a day, while Xanax is usually taken several times a day. Buspar may be used long-term for anxiety symptoms, but Xanax is often only used for a short period of time. Xanax generally has more serious side effects, such as drowsiness, dizziness, and coordination problems. It’s also a controlled substance, which means it can lead to dependence and misuse. It can also cause withdrawal symptoms if stopped abruptly, and has more serious drug interactions than Buspar. For example, combining Xanax with certain substances, such as opioids or alcohol, can lead to slowed breathing and overdose. While Buspar can cause dizziness and headaches, it isn’t known to cause withdrawal symptoms, misuse, or overdose.
