The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Nausea (15%)
- Vomiting (7%)
- Headache (5%)
- Dizziness (3%)
Less Common Side Effects
- Sleepiness
- Constipation
- Indigestion or heartburn
- Swollen face
- Itchiness
Combogesic serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Stomach bleeding: blood in your vomit, stool that looks like black coffee grounds, pain in your stomach that doesn't go away
- Liver damage: nausea, vomiting, loss of appetite, severe stomach pain, yellowing of skin or eyes
- Heart attack: dizziness, tiredness, cold sweat, trouble breathing, chest pain or tightness that spreads to the arm or jaw
- Stroke: severe headache, blurred vision, trouble speaking, trouble walking, weakness on one side of the body, drooping face
- Heart failure: trouble breathing, tiredness, dizziness, swelling, sudden weight gain
- Kidney damage: little or no urination, needing to urinate more often than usual, tiredness, dry and itchy skin, loss of appetite, muscle cramps, swelling in the ankles or feet
- Serious allergic reaction or skin reaction: rash; hives; painful blisters; peeling skin; trouble breathing; swelling of the face, lips, or throat; fever
Source: DailyMed
The following Combogesic side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
- Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
- Heart failure—shortness of breath, swelling of the ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue
- Increase in blood pressure
- Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Rash, fever, and swollen lymph nodes
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
- Round red or dark patches on the skin that may itch, burn, and blister
- Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Headache
- Loss of appetite
- Nausea
- Trouble sleeping
- Upset stomach
Other Combogesic articles
