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Vaptans

Vaptans, or vasopressin receptor antagonists, are used to treat hyponatremia, or abnomally low levels of sodium in the blood. Vaptans can also slow the progression of certain kidney diseases. They work by inhibiting the effect of vasopressin in the body. Vasopressin is a hormone that helps regulate the body's water retention, blood pressure, blood sodium levels, and kidney function.

Why are vaptans prescribed?

  1. Hyponatremia (100%)
  2. Kidney Disease (0%)

Key takeaways

Vaptans are used to treat low blood sodium levels and autosomal dominant polycystic kidney disease (ADPKD). They work by blocking the action of vasopressin, a hormone that regulates water balance in your body, which helps to increase the amount of water excreted in your urine and raise your blood sodium levels. These medications are available in oral forms. Examples include tolvaptan (Samsca, Jynarque). You can choose the form that best fits your needs.

Prices for popular Vaptans medications
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Samsca (tolvaptan)

TOLVAPTAN treats low sodium levels in your body. It works by helping your kidneys remove more fluid from your blood through the urine without losing too much sodium. This helps your body maintain the right amount of sodium it needs.
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Jynarque

Jyrnarque is a used to slow kidney function decline in adults who are at risk for rapidly progressing autosomal dominant polycystic kidney disease. There are currently no generic alternatives to Jynarque. It is covered by most Medicare and insurance plans.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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