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Pyruvate Kinase Activator

Pyruvate kinase activators are used to treat hemolytic anemia. Pyruvate kinase activators work by increasing pyruvate kinase activity, and in turn, increasing the amount of energy available to cells.

Why are pyruvate kinase activator prescribed?

  1. Anemia (100%)

Key takeaways

Pyruvate kinase activators are used to treat anemia caused by pyruvate kinase deficiency, a rare genetic disorder that affects red blood cells. These medications work by activating the pyruvate kinase enzyme, which helps improve the energy production in red blood cells, reducing symptoms of anemia. An example of this type of medication is mitapivat (Pyrukynd), which is available in oral form.

Prices for popular Pyruvate Kinase Activator medications
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Pyrukynd

as low as$24,660
MITAPIVAT treats hemolytic anemia caused by pyruvate kinase deficiency. It works by stopping red blood cells from breaking down too quickly. This decreases symptoms and the need for blood transfusions.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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