PARP inhibitors are used to treat ovarian cancer, breast cancer, and prostate cancer. They also have other uses, such as treating pancreatic cancer. PARP inhibitors work by blocking PARP proteins, which normally help repair damaged DNA in cells. By blocking this protein, PARP inhibitors make it harder for cancer cells to repair themselves, leading to their death. These medications are available in oral form. Examples include Lynparza (olaparib), Rubraca (rucaparib), and Talzenna (talazoparib).