ACE inhibitor / calcium channel blocker combinations are used to treat high blood pressure. These medications work by relaxing your blood vessels and reducing the workload on your heart. ACE inhibitors block a chemical that tightens blood vessels, while calcium channel blockers prevent calcium from entering cells of the heart and blood vessels, helping to lower blood pressure. These medications are usually taken as oral pills. Examples include amlodipine/benazepril (Lotrel), trandolapril/verapamil, and perindopril/amlodipine (Prestalia). You can take these medications to help manage your condition effectively.