Specialty Drug
C1 INHIBITOR, HUMAN (C1 in HIB i ter, HYOO muhn) helps to prevent angioedema attacks. Compare C1 inhibitors.

Cinryze Medicare Coverage


Does Medicare cover Cinryze?

96% of Medicare Part D and Medicare Advantage plans cover this drug.

How much is my Cinryze co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…

Donut Hole
Post-Donut Hole
Co-Pay Range
$2592 – $63452
In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.
Co-Pay Range
$648 – $63452
In the Typical co-pay stage, your deductible has been satisfied, and Medicare pays the majority of your drug costs.
Co-Pay Range
$961 – $63452
In the Donut Hole (also called the Coverage Gap) stage, you’ll pay more for your prescriptions. In 2016, the Donut Hole begins once you’ve spent $3,310 in one year.
Co-Pay Range
$130 – $63452
In the Post-Donut Hole (also called Catastrophic Coverage) stage, Medicare will cover most of your drug costs. In 2016, this stage begins once you have spent $4,850.
Want an exact price for your co-pay?

Ways to Save on Cinryze

Here are some ways that may lower the cost of your Cinryze prescription.

Find Your Cinryze Medicare Co-Pay

Here are average co-pays for some of the most popular Medicare plans. Be sure to add your plan to see your specific co-pay. If a price is shown in red, GoodRx has found discount prices that are lower than your Medicare co-pay.

Average Co-Pay for 20 vials of Cinryze 500 units

Medicare Plan Name Average Co-Pay
AARP MedicareRx Preferred (PDP) $1154
AARP MedicareRx Saver Plus (PDP) $4417
AARP MedicareRx Walgreens (PDP)Lower price available $59762
Aetna Medicare Rx Saver (PDP) $720
Anthem Blue Cross MedicareRx Plus (PDP)Lower price available $63452
Anthem MediBlue Essential (HMO) $879
CareMore Value Plus (HMO) $1550
Cigna-HealthSpring Preferred (HMO) $814
EnvisionRxPlus (PDP) $713
Express Scripts Medicare - Choice (PDP) $733
Express Scripts Medicare - Value (PDP) $705
First Health Part D Value Plus (PDP) $951
Humana Enhanced (PDP) $869
Humana Preferred Rx Plan (PDP) $659
Humana Walmart Rx Plan (PDP) $659
Kaiser Permanente Medicare Plus Std w/Part D (AB) (Cost) $956
MedicareBlue Rx Standard (PDP) $748
SilverScript Plus (PDP) $974
Symphonix Value Rx (PDP)Lower price available $63452
TexanPlus Classic (HMO) $2455
Don't see your Medicare plan above?

Find and configure your plan to see exact co-pay prices for your meds.

Cinryze Medicare Formulary Information & Restrictions

Are there any restrictions on coverage?

Some Medicare plans have restrictions on coverage of Cinryze that may include:

Prior Authorization

Most Medicare plans will require you to obtain their authorization before they will provide coverage for this prescription. You’ll need to contact your plan and they may require you to have your doctor fill out paperwork indicating why you need this prescription. If you do not receive authorization or don’t want to go through this process, you may want to consider using a GoodRx discount instead of Medicare to find the best price for this prescription.

What drug tier is Cinryze typically on?

Tier 5

Medicare plans typically list Cinryze in Tier 5 of their formulary. Tier 5 drugs are usually non-preferred brand-name drugs. Tier 5 drugs cost more than Tier 1, 2, 3 and 4 drugs.

Does your plan have restrictions?

See discount prices that can save you money when your Medicare plan doesn't work for you.

Medicare prices are provided by the Centers for Medicare and Medicaid Services (CMS). They are accurate as-of January 2017 and the information may be updated. If you encounter any issues, please let us know.
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