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Capcof

chlorpheniramine / codeine / phenylephrine
Used for Nasal Congestion, Allergic Rhinitis, Cold Symptoms, Cough
Used for Nasal Congestion, Allergic Rhinitis, Cold Symptoms, Cough

CapCof is a combination of three medications: chlorpheniramine (antihistamine), codeine (opioid), and phenylephrine (decongestant). It's used to treat symptoms from allergies and the common cold.

Last reviewed on March 30, 2022
CapCof is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.
basics-icon

What is CapCof?

What is CapCof used for?

Short-term relief of symptoms due to the common cold or allergies:

  • Runny nose

  • Sneezing

  • Itchy nose or throat

  • Itchy, watery eyes

  • Cough

  • Stuffy nose (nasal congestion)

  • Nasal passage swelling

How CapCof works

CapCof is a combination of three medications that work together to relieve symptoms caused by the common cold and allergies.

  • Chlorpheniramine is an antihistamine. It blocks a natural substance in your body called histamine that normally causes allergy symptoms. By blocking histamine, chlorpheniramine relieves runny or itchy nose, sneezing, and watery eyes.

  • Codeine is an opioid that works in your brain to lower your urge to cough.

  • Phenylephrine is a decongestant that clears your sinuses to relieve sinus pressure.

Are you looking for information on Advil Allergy and Congestion (chlorpheniramine / ibuprofen / phenylephrine) or [Histex AC (codeine / phenylephrine / triprolidine)(https://www.goodrx.com/histex-ac/what-is) instead?

Drug Facts

Common BrandsCapCof, Maxi-Tuss CD
Drug ClassAntihistamine / Opioid / Decongestant
Controlled Substance ClassificationSchedule V
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Avg retail price
$104.02(save 60.64%)
GoodRx discount
$40.94
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What are the risks and warnings for CapCof?

CapCof can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

risk-warning

Accidental overdose

CapCof contains an antihistamine (chlorpheniramine), an opioid (codeine), and a decongestant (phenylephrine), which are ingredients found in many other prescription and over-the-counter products. Using more than one medication containing an antihistamine, an opioid, or a decongestant or taking more CapCof than prescribed can lead to serious complications. Such complications include an accidental overdose and serious side effects, like slowed breathing, seizures, hallucinations (seeing things that aren't real), or even death.

Tell your provider or pharmacist about the medications you take before starting CapCof to make sure it's safe for you. Don't start any new medications while taking CapCof without talking to your provider or pharmacist.

To prevent an accidental overdose, read package labels carefully. If you're not sure if a product has an antihistamine, an opioid, or a decongestant, ask your pharmacist. If you or your loved one experiences an accidental overdose, get medical help right away or contact a poison control center at 1-800-222-1222.

risk-warning

Sleepiness

  • Risk factors: Drinking alcohol while taking CapCof | Taking other medications that cause sleepiness | Age 65 and older

    CapCof can make you very sleepy, which can affect your ability to focus, think, or react. This side effect is more likely to happen or be more intense if you're over 65 years old, drink alcohol while taking this medication, or take other medications that cause sleepiness (e.g., opioids, benzodiazepines, sleep medications). Don't drive or operate machinery until you know how this medication affects you.

    risk-warning

    Worsening of medical conditions

    • Risk factors: Breathing problems (e.g., emphysema, chronic bronchitis, other lung conditions) or shortness of breath | Cough from smoking, asthma, or emphysema | Mucus-producing cough | Heart disease or high blood pressure | Diabetes | Glaucoma | Urinary conditions

      Don't take CapCof if you have any of the risk factors listed above unless your provider said it's safe to do so. Taking CapCof can worsen your condition(s) and cause serious side effects. Make sure your provider knows about all medical conditions you have or have had in the past before starting CapCof.

      basics-icon

      What are the side effects of CapCof?

      The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

      Common Side Effects

      Other Side Effects

      • Restlessness
      • Headache

      Serious Side Effects

      Contact your healthcare provider immediately if you experience any of the following.
      • Excessive sleepiness or dizziness
      • Slowed breathing
      • Signs of an overdose: slowed breathing, not responding to sound or touch, pale or blue skin, seizures, hallucinations

      Source: DailyMed

      pros-and-cons

      Pros and cons of CapCof

      thumbs-up

      Pros

      Can treat a wide variety of common cold or allergy symptoms

      More convenient to take three medications in one liquid product

      Can take with or without food

      thumbs-down

      Cons

      Needs to be taken every 4 hours

      Has potential for abuse and misuse (it's a controlled medication)

      Available as a liquid only

      pharmacist-tips

      Pharmacist tips for CapCof

      pharmacist
      • You can take CapCof with or without food.

        • Use a medication dose cup or an oral syringe to measure your dose of CapCof correctly. Don't use household spoons, because they might not be accurate and cause you to take the wrong dose.

          • CapCof can make you sleepy or dizzy during the day, which can affect your ability to focus, think, or react. Don't drive or operate machinery until you know how the medication affects you.

            • While CapCof usually makes adults sleepy, it's possible for children who use CapCof to become overly excited or energetic. If this happens to your child, speak to your child's provider.

              • Avoid drinking alcohol while taking CapCof, because this raises your risk of sleepiness and dizziness.

                • CapCof can cause constipation. Make sure to eat a healthy diet and drink plenty of water. If you become constipated, there are several over-the-counter options available, such as stimulant laxatives and stool softeners, to help treat it. If you're having constipation that won't go away, contact your provider.

                  • Stop using CapCof and contact your provider if you experience any of the following: cough or nasal congestion that gets worse or lasts more than 7 days; cough with a fever, rash, or headache that won't go away; feeling nervous or dizzy; having trouble sleeping; or if any new symptoms appear while taking CapCof. These might be signs of another underlying medical condition that CapCof might not be appropriate for.

                    • Tell your provider or pharmacist about all the medications you or your child is taking to make sure CapCof is safe to take. While you're using CapCof, talk to your provider or pharmacist first before starting any new medications, especially those containing opioids, decongestants, or antihistamines. Taking these medications with CapCof can raise your risk of overdose and severe side effects, including slowed breathing, dizziness, and sleepiness.

                      faqs

                      Frequently asked questions about CapCof

                      How do I know if CapCof is safe for me to take?
                      CapCof is generally safe to take, but it's not the best choice for everyone. Ask your provider before using CapCof if you have any of the following medical conditions: breathing problems (e.g., emphysema, chronic bronchitis, other lung conditions) or shortness of breath; a cough that occurs with smoking, asthma, or emphysema; glaucoma; trouble urinating due to a large prostate gland, heart disease or high blood pressure; or diabetes. CapCof can make these conditions worse. In addition, don't give [EDITOR|DRUG_DISPLAY_NAME]] to a child who's taking other medications or if you're 65 years of age and older without talking to your provider first to make sure it's safe to use.
                      Why is CapCof a controlled medication?
                      CapCof is a schedule V controlled medication, because it contains codeine, which is an opioid. Opioids have potential for abuse. "Abuse" means using a medication for certain physical or psychological effects that aren't related to the treatment of a medical condition diagnosed by your provider. Make sure to store CapCof in a safe place away from children, since it can cause life-threatening breathing problems if accidentally taken by a child.
                      Can I use CapCof only when I need it?
                      Yes, you can use CapCof as needed for your symptoms. Use the lowest dose for the shortest amount of time.
                      Can I use CapCof if I'm pregnant or breastfeeding?
                      If you're pregnant or breastfeeding, don't use CapCof until you've talked to your provider first to make sure it's safe for you to take.
                      Why can't children under 6 years old use CapCof?
                      Children under 6 years old can't use CapCof because their risk for overdose and side effects is higher. If your child is having common cold or allergy symptoms, ask your child's provider or pharmacist for other options.
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                      dosage

                      CapCof dosage forms

                      The average cost for 1 bottle of 473ml of 2mg/10mg/5mg/5ml of CapCof is $40.94 with a free GoodRx coupon. This is 60.64% off the average retail price of $104.02.
                      bottle of liquid
                      Bottle of liquid
                      DosageQuantityPrice as low asPrice per unit
                      473ml of 2mg/10mg/5mg/5ml1 bottle$40.94$40.94

                      Typical dosing for CapCof

                      It's recommended to use the lowest dose possible for the shortest duration of time to manage your symptoms.

                      Capcof liquid: Each 5 mL contains 2 mg of chlorpheniramine, 10 mg of codeine, and 5 mg of phenylephrine.

                      • Adults and children age 12 years and up: The typical dose is 2 teaspoonfuls (10 mL) by mouth every 4 hours. Don't use more than 12 teaspoonfuls (60 mL) in a 24-hour period.

                      • Children age 6 to 11 years old: The typical dose is 1 teaspoonful (5 mL) by mouth every 4 hours. Don't use more than 6 teaspoonfuls (30 mL) in a 24-hour period.

                      • Children under 6 years old: Ask your child's provider.

                      Maxi-Tuss CD liquid: Each 5 mL contains 4 mg of chlorpheniramine, 10 mg of codeine, and 10 mg of phenylephrine.

                      • Adults and children age 12 years and up: The typical dose is 1 teaspoonful (5 mL) by mouth every 4 hours. Don't use more than 6 teaspoonfuls (30 mL) in a 24-hour period.

                      • Children age 6 to 11 years old: The typical dose is one-half teaspoonful (2.5 mL) by mouth every 4 hours. Don't use more than 3 teaspoonfuls (15 mL) in a 24-hour period.

                      • Children under 6 years old: Ask your child's provider.

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                      contraindications-icon

                      CapCof contraindications

                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because CapCof will not be safe for you to take.
                      • Currently take or have taken an MAOI in the last 14 days

                      alternatives

                      What are alternatives to CapCof?

                      There are a number of medications that your doctor can prescribe in place of CapCof. Compare a few possible alternatives below.
                      CapCof
                      Used for:

                      Short-term relief of symptoms due to the common cold or allergies:

                      • Runny nose

                      • Sneezing

                      • Itchy nose or throat

                      • Itchy, watery eyes

                      • Cough

                      • Stuffy nose (nasal congestion)

                      • Nasal passage swelling

                      $40.94 Lowest GoodRx priceView Prices
                      Used for:
                      • Cough

                      • Runny nose

                      • Sneezing

                      • Itchy nose or throat

                      • Itchy or watery eyes

                      • Stuffy nose (nasal congestion)

                      • Sinus congestion

                      $11.71 Lowest GoodRx priceView Prices
                      Used for:
                      • Cough from throat and lung irritation

                      • Runny nose

                      • Sneezing

                      • Itchy or watery eyes

                      • Itching of the nose or throat

                      • Stuffy nose (nasal congestion)

                      $5.49 Lowest GoodRx priceView Prices

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