Skip to main content
Butalbital/Acetaminophen

Butalbital/Acetaminophen Side Effects

Cydnee Ng, PharmDAshley Wong, PharmD
Reviewed by Cydnee Ng, PharmD, Ashley Wong, PharmD
Last reviewed on September 17, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Sleepiness
  • Lightheadedness
  • Dizziness
  • Shortness of breath
  • Nausea
  • Vomiting
  • Stomach pain
  • Lack of coordination and alertness

Butalbital/Acetaminophen serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Overdose: Not responding to sound or touch, extreme sleepiness, slowed breathing, confusion, stomach pain, dark urine, yellowing of your skin or eyes, sweating
  • Withdrawal: Seizures, delusions, restlessness, trouble sleeping, shakiness
  • Serious skin reactions: Reddening or peeling of the skin, painful rash, fluid-filled blisters
  • Serious allergic reactions: Trouble breathing, itchiness, swelling of the face, mouth, or throat

Source: DailyMed

The following Butalbital/Acetaminophen side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Bleeding or crusting sores on lips

chest pain

fever with or without chills

hive-like swellings (large) on eyelids, face, lips, and/or tongue

muscle cramps or pain

red, thickened, or scaly skin

shortness of breath, troubled breathing, tightness in chest, or wheezing

skin rash, itching, or hives

sores, ulcers, or white spots in mouth (painful)

Symptoms of overdose

Anxiety, confusion, excitement, irritability, nervousness, restlessness, or trouble in sleeping (severe, especially with products containing caffeine)

convulsions (seizures) (for products containing caffeine)

diarrhea, especially if occurring together with increased sweating, loss of appetite, and stomach cramps or pain

dizziness, lightheadedness, drowsiness, or weakness, (severe)

frequent urination (for products containing caffeine)

hallucinations (seeing, hearing, or feeling things that are not there)

increased sensitivity to touch or pain (for products containing caffeine)

muscle trembling or twitching (for products containing caffeine)

nausea or vomiting, sometimes with blood

ringing or other sounds in ears (for products containing caffeine)

seeing flashes of "zig-zag" lights (for products containing caffeine)

shortness of breath or unusually slow or troubled breathing

slow, fast, or irregular heartbeat

slurred speech

staggering

swelling, pain, or tenderness in the upper abdomen or stomach area

unusual movements of the eyes

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

Confusion (mild)

mental depression

unusual excitement (mild)

Rare

Bloody or black, tarry stools

bloody urine

pinpoint red spots on skin

swollen or painful glands

unusual bleeding or bruising

unusual tiredness or weakness (mild

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Bloated or "gassy" feeling

dizziness or lightheadedness (mild)

drowsiness (mild)

nausea, vomiting, or stomach pain (occurring without other symptoms of overdose)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

GoodRx icon

Other Barbiturate / Acetaminophen Combinations side effects articles

why trust our exports reliability shield

Why trust our experts?

Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.
Ashley Wong, PharmD, is a licensed pharmacist in California. She has over 6 years of experience providing drug information.

Was this page helpful?