Azacitidine Side Effects
What should I watch for?
Visit your doctor for checks on your progress. This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
You may need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine and for 6 months after the last dose. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after the last dose. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine and for 1 week after the last dose.
This medicine may interfere with the ability to have a child. Talk with your doctor or health care professional if you are concerned about your fertility.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Black, tarry stools
blood in the urine or stools
body aches or pain
burning or stinging of the skin
frequent urge to urinate
loss of voice
lower back or side pain
pain or tenderness around the eyes and cheekbones
painful cold sores or blisters on the lips, nose, eyes, or genitals
painful or difficult urination
pain, redness, swelling, tenderness, warmth on the skin
pinpoint red spots on the skin
puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
sores, ulcers, or white spots on lips or in mouth
tender, swollen glands in the neck
tightness in the chest
troubled breathing with exertion
unusual bleeding or bruising
unusual tiredness or weakness
Get emergency help immediately if any of the following symptoms of overdose occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Acid or sour stomach
bleeding after defecation
bumps on the skin
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
burning while urinating
difficulty having a bowel movement (stool)
difficulty with moving
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
feeling of discomfort or illness
feeling of sluggishness
feeling sad or empty
feeling unusually cold
full or bloated feeling or pressure in the stomach
inflamed tissue from infection at the injection site
injection site bruising
itching at injection site
lack of appetite
large, flat, blue or purplish patches in the skin
loss of interest or pleasure
pain in the joints
post procedural hemorrhage
redness of the skin
small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope
small lumps under the skin
small red or purple spots in the mouth
soreness or discomfort to touch or pressure on the stomach
stomach discomfort upset or pain
swelling of abdominal or stomach area
swelling of the hands, ankles, feet, or lower legs
swelling or inflammation of the mouth
swelling with pits or depressions visible on the skin
uncomfortable swelling around the anus
unusually warm skin
upper abdominal or stomach pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.