The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Application site irritation (7%)
- Application site redness (5%)
- Headache (5%)
- High red blood cell count (4%)
- Diarrhea (3%)
- Vomiting (3%)
- Rise in prostate-specific antigen (PSA, 1%)
Less Common Side Effects
- Application site swelling
- Application site warmth
- Skin redness
- High blood pressure
- High blood sugar
- Acne
- More tears
- Common cold
- Anger
- Anxiety
- Weakness
- Breast tenderness
Axiron serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Heart attack: chest pain, cold sweats, left arm pain, difficulty breathing
- Stroke: face drooping, trouble seeing, walking, speaking, weakness on one side of the body
- Blood clots: legs (pain, swelling, warm to touch, redness), lungs (trouble breathing, chest pain, cough)
- Withdrawal: depression, fatigue, craving, restlessness, irritability, lack of appetite, trouble sleeping (insomnia), lower sex drive, and low testosterone
- Liver damage: stomach pain, nausea, vomiting, yellowing of the skin, yellowing of the whites of the eyes, light-colored stools, dark urine, weight loss
Source: DailyMed
The following Axiron side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Bloating or swelling of the face, arms, hands, lower legs, or feet
blurred vision
feeling faint, dizzy, or lightheaded
feeling of warmth or heat
flushing or redness of the skin, especially on the face and neck
frequent strong or increased urge to urinate
headache
nervousness
pain, redness, or swelling in the arm or leg
pounding in the ears
slow or fast heartbeat
sweating
swelling of the breasts or breast soreness in both females and males
tingling of the hands or feet
unusual weight gain or loss
waking to urinate at night
Incidence not known
Aggressive behavior
bluish lips or skin
decrease in testicle size
development of pubic hair
difficult or labored breathing
dizziness or lightheadedness
enlargement of the clitoris or penis
fainting
fast heartbeat
not breathing
pain, redness, or swelling in the arm or leg
painful or prolonged erection of the penis
tightness in the chest
troubled breathing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Blemishes on the skin
burning, itching, redness, skin rash, swelling, or soreness at the application site
Less common
Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
crying
decreased interest in sexual intercourse
discoloration of the hair
false or unusual sense of well-being
inability to have or keep an erection
lack or loss of strength
loss in sexual ability, desire, drive, or performance
loss of memory
paranoia
problems with memory
quick to react or overreact emotionally
rapidly changing moods
thinning of the hair
Incidence not known
Increased in sexual ability, desire, drive, or performance
trouble sleeping
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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