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Danazol

Danazol Side Effects

Dalga Surofchy, PharmD, APhAllison Gourley, PharmD
Reviewed by Dalga Surofchy, PharmD, APh, Allison Gourley, PharmD
Last reviewed on May 31, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Weight gain
  • Acne
  • Swelling
  • Deepening of voice
  • Sweating or flushing

Less Common Side Effects

  • Liver problems

Danazol serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reaction
  • Sudden liver problems
  • Clotting and deadly strokes

Source: DailyMed

The following Danazol side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

For both females and males

Less common

Acne

dark-colored urine

increased oiliness of the hair or skin

muscle cramps or spasms

rapid weight gain

swelling of the feet or lower legs

unusual tiredness or weakness

Rare

Bleeding gums

bloating, pain, or tenderness of the abdomen or stomach

blood in the urine

burning, numbness, pain, or tingling in all fingers except the smallest finger

changes in vision

chest pain

chills

complete or partial numbness or weakness on one side of body

cough

coughing up blood

diarrhea

difficulty with speaking

difficulty with swallowing

discharge from the nipple

eye pain

fast heartbeat

fever

headache

hives or other skin rash

joint pain

light-colored stools

loss of appetite (continuing)

loss of muscle coordination

more frequent nosebleeds

muscle aches

nausea

purple- or red-colored, or other spots on the body or inside the mouth or nose

restlessness

shortness of breath

sore throat

sweating

tingling, numbness, or weakness in the legs, which may move upward to the arms, trunk, or face

unusual bruising or bleeding

unusual tiredness, weakness, or general feeling of illness

vomiting

yellow eyes or skin

For females only

More common

Decrease in the breast size

irregular menstrual periods

weight gain

Rare

Enlarged clitoris

hoarseness or deepening of voice

unnatural hair growth

For males only

Rare

Changes in semen

decrease in the size of the testicles

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For both females and males

Less common

Flushing or redness of the skin

mood or mental changes

nervousness

Rare

Increased sensitivity of the skin to sunlight

For females only

Less common

Burning, dryness, or itching of the vagina

vaginal bleeding

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Dalga Surofchy, PharmD, APh, is an Advanced Practicing Pharmacist working in San Diego, CA. He holds a bachelor’s degree in biology from the University of California, Berkeley and a Doctor of Pharmacy from the University of California, San Francisco.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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