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Amitiza (lubiprostone) is a laxative used to treat chronic constipation and constipation caused by opioids. Amitiza is the only drug in the chloride channel activators class. There are currently no generic alternatives to Amitiza.
Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Amitiza is covered by most Medicare and insurance plans.
With the Patient Assistance Program from Takeda, you can receive your medication at no cost.


| Dosage | Quantity | Retail price | GoodRx price |
|---|
| 8mcg | 60 capsules | $489.90 | $407.06 |
| 24mcg | 60 capsules | $484.01 | $405.93 |
GoodRx coupon prices last updated on 05/02/26.