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Alosetron

Alosetron Side Effects

Kristianne Hannemann, PharmDConnie Zheng, PharmD
Reviewed by Kristianne Hannemann, PharmD, Connie Zheng, PharmD
Last reviewed on September 26, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Constipation (29%)
  • Abdominal discomfort and pain (7%)
  • Nausea (6%)

Less Common Side Effects

  • Bloating
  • Heartburn, acid reflux
  • Hemorrhoids

Alosetron serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Ischemic colitis: fever, bloating, worsening stomach pain, rectal bleeding, blood in stool, bloody diarrhea
  • Severe constipation

Source: DailyMed

The following Alosetron side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Constipation

Rare

Bloody diarrhea

new or worsening stomach pain or discomfort

rectal bleeding

Incidence not known

Abdominal or stomach pain, cramping, or burning

black, tarry stools

diarrhea

fever

heartburn

indigestion

nausea

vomiting with or without blood or material that looks like coffee grounds

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Clumsiness, unsteadiness, trembling, or other problems with muscle control or coordination

convulsions (seizures)

difficulty breathing

shakiness and unsteady walk

withdrawn or socially detached behavior

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Bleeding after bowel movement

full or bloated feeling

pressure in the stomach

swelling of abdominal or stomach area

uncomfortable swelling around rectal area

Incidence not known

Headache

skin rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.
Connie Zheng, PharmD, is a drug information pharmacist at GoodRx and a licensed pharmacist in California. She has over 6 years of experience working in independent pharmacies.

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