Prescription Prices and Coupons from GoodRx
Type your drug name (like Atorvastatin, Sildenafil, etc)
Specialty Drug
TOCILIZUMAB is a monoclonal antibody. It is used to treat rheumatoid arthritis, juvenile idiopathic arthritis, giant cell arteritis, and cytokine release syndrome due to chimeric antigen receptor (CAR) T-cell treatment. Compare interleukin antagonists.
Prescription Settings
20ml of 20mg/ml
6 vials
20ml of 20mg/ml
6 vials

Actemra Side Effects

What should I watch for?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Your condition will be monitored carefully while you are receiving this medicine.

You will be tested for tuberculosis (TB) before you start this medicine. If your doctor prescribes any medicine for TB, you should start taking the TB medicine before starting this medicine. Make sure to finish the full course of TB medicine.

Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.

You may need blood work done while you are taking this medicine.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools

bloody or cloudy urine

blurred vision

body aches or pain

chest pain


cough with or without mucus


difficult, burning, or painful urination

difficulty breathing

difficulty swallowing


ear congestion

fast heartbeat

feeling of warmth


frequent urge to urinate


hives, itching, skin rash

loss of appetite

loss of consciousness

loss of voice

lower back or side pain

nasal congestion



pain or tenderness around the eyes and cheekbones

painful blisters on the trunk of the body

pale skin

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

redness of the face, neck, arms, and occasionally, upper chest

slow or fast heartbeat


sore throat

stomach pain

stuffy or runny nose

sudden sweating

tightness of the chest

ulcers, sores, or white spots in the mouth

unusual bleeding or bruising

unusual tiredness or weakness

Less common

Accumulation of pus

bladder pain

burning feeling in the chest or stomach


dark urine

decrease in height

difficulty moving

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fast, irregular, pounding, or racing heartbeat or pulse

feeling hot

general feeling of discomfort or illness



itching, pain, redness, swelling, tenderness, or warmth on the skin at the injection site

joint pain

light-colored stools

muscle ache, pain, cramp, or stiffness

pain in the back, ribs, arms, legs, or groin or genitals

severe stomach pain

sharp back pain just below the ribs


stomach upset


swollen joints

swollen, painful, or tender lymph glands in the face, neck, armpit, or groin

swollen, red, or tender area of infection

tenderness in the stomach area

trouble with sleeping

troubled breathing with exertion

unexplained runny nose or sneezing


yellow eyes and skin



changes in skin color

coughing or spitting up blood


gaseous stomach pain


neck pain

night sweats

noisy breathing

rapid, shallow breathing

recurrent fever

red, tender, or oozing skin at the wounded area

sudden high fever or low-grade fever for months

swelling of the foot or leg

weight loss

Incidence not known

Dilated neck veins

extreme tiredness or weakness

severe stomach pain, cramping, or burning

swelling of the face, fingers, feet, or lower legs

vomiting of material that looks like coffee grounds, severe and continuous

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Burning, dry, or itching eyes


discharge, excessive tearing

redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

skin rash, encrusted, scaly and oozing

swelling or inflammation of the mouth

Less common

Abnormal or decreased touch sensation

bleeding or redness and swelling of the gums

blemishes on the skin

bloody eye

chapped, red, or swollen lips


feeling of constant movement of self or surroundings

irritation in the mouth

loose teeth

persistent breath odor or bad taste in your mouth


redness or swelling in the ear

scaling, redness, burning, pain, or other signs of inflammation on the lips

sensation of spinning

sore mouth or tongue

white patches in the mouth or on the tongue


Bleeding after passing stool


bloody nose

burning, numbness, tingling, or painful sensations

change in hearing

continuing ringing or buzzing or other unexplained noise in the ears

coughing or spitting up blood

decreased vision or other changes in vision

dry mouth

ear drainage

flushed, dry skin

fruit-like breath odor

hearing loss

increased hunger, thirst, urination

itching ears

uncomfortable swelling around the anus

unexplained weight loss

unsteadiness or awkwardness

weakness in the arms, hands, legs, or feet

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Copyright ©2018 GoodRx, Inc.
GoodRx is not sponsored by or affiliated with any of the pharmacies identified in its price comparisons. All trademarks, brands, logos and copyright images are property of their respective owners and rights holders and are used solely to represent the products of these rights holders. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment.
In all states except Tennessee, GoodRx is considered a marketer of prescription discount cards, and is not required to register as a discount card provider. In Tennessee, GoodRx is registered as a Prescription Drug Discount Plan Operator.
LegitScript SealNABP SealBBB Seal
The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products.