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Actemra

Actemra Dosage

Robert Chad Hakim, PharmD, BCCCPConnie Zheng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Connie Zheng, PharmD
Last reviewed on October 11, 2023

The average cost for 1 vial of 4ml of 20mg/ml of Actemra is $575.78 with a free GoodRx coupon.

vialVial

Dosage

Quantity

Price as low as

Price per unit

4ml of 20mg/ml

1 vial

$575.78

$575.78

10ml of 20mg/ml

1 vial

$1,426.71

$1,426.71

20ml of 20mg/ml

1 vial

$2,844.91

$2,844.91

syringeSyringe

Dosage

Quantity

Price as low as

Price per unit

162mg/0.9ml

4 syringes

$5,584.92

$1,396.23

autoinjectorAutoinjector

Dosage

Quantity

Price as low as

Price per unit

162mg/0.9ml

2 autoinjectors

$2,796.71

$1,398.36

Typical dosage for Actemra

Actemra is given as an infusion through the veins (intravenous or IV) over 1 hour. It can also be given as an injection under the skin (subcutaneous or SC).

Your provider will decide your dose based on how well the medication is working for you, your body weight, if it's being given as an IV or SC injection, and if it's causing side effects.

  • Rheumatoid arthritis:
    • IV: The typical dose is 4 mg/kg for the first dose, then 4 mg/kg to 8 mg/kg every month. The maximum dose is 800 mg per infusion.
    • SC:
      • Weight less than 220 lbs: The typical dose is 162 mg every 1 to 2 weeks.
      • Weight 220 lbs or more: The typical dose is 162 mg every week.

  • Giant cell arteritis
    • IV: The typical dose is 6 mg/kg every month. The maximum dose is 600 mg per infusion.
    • SC: The typical dose is 162 mg every 1 to 2 weeks.

  • Systemic sclerosis-associated interstitial lung disease
    • SC: The typical dose is 162 mg every week.

  • Polyarticular juvenile idiopathic arthritis
    • IV:
      • Weight less than 66 lbs: The typical dose is 10 mg/kg every month.
      • Weight 66 lbs or more: The typical dose is 8 mg/kg every month.
    • SC:
      • Weight less than 66 lbs: The typical dose is 162 mg once every 3 weeks.
      • Weight 66 lbs or more: The typical dose is 162 mg once every 2 weeks.

  • Systemic juvenile idiopathic arthritis
    • IV:
      • Weight less than 66 lbs: The typical dose is 12 mg/kg every 2 weeks.
      • Weight 66 lbs or more: The typical dose is 8 mg/kg every 2 weeks.
    • SC:
      • Weight less than 66 lbs: The typical dose is 162 mg once every 2 weeks.
      • Weight 66 lbs or more: The typical dose is 162 mg once a week.

  • Cytokine release syndrome
    • IV:
      • Weight less than 66 lbs: The typical dose is 12 mg/kg given as a single dose. If there's no improvement, your provider can give you up to 3 more doses, at least 8 hours apart. The maximum dose is 800 mg per infusion.
      • Weight 66 lbs or more: The typical dose is 8 mg/kg given as a single dose. If there's no improvement, your provider can give you up to 3 more doses, at least 8 hours apart. The maximum dose is 800 mg per infusion.

  • COVID-19
    • IV: The typical dose is 8 mg/kg given as a single dose. If there's no improvement, your provider can give you one more dose, at least 8 hours after your first dose. The maximum dose is 800 mg per infusion.

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