Vyepti Dosages for Adults: Your GoodRx Guide

Blurry vision, constant nausea, and crippling pain are all common migraine symptoms. And chronic migraines can cause symptoms like these more than 15 times per month. So it’s no surprise that medications used to prevent chronic migraines can be life-changing treatments for some people.

Vyepti (eptinezumab) is one medication that helps prevent migraines in adults. But it’s not a pill you take every day like other medications. Let’s take a look at the recommended Vyepti dosage for adults and how it’s given. This can help you know what to expect if your healthcare provider prescribes Vyepti for your chronic migraines. 

What’s the typical Vyepti dosage for adults?

The recommended Vyepti dosage for adults is 100 mg every 3 months (12 weeks). If that isn’t effective, your healthcare provider may try a higher dose of 300 mg every 3 months. Doses higher than 300 mg every 3 months aren’t recommended.

You’ll receive Vyepti as an infusion into a vein (IV). So you’ll need to go to an infusion center or healthcare provider’s office to receive it. You can’t give yourself Vyepti treatments at home.

How long does a Vyepti infusion take?

A Vyepti infusion takes about 30 minutes. But your appointment will likely take a bit longer than that, since it takes time to prepare your dose and set up the infusion.

Be sure to wear comfortable clothes that provide easy access to your arm — layers often work well. Infusions can make some people feel chilly, so a sweater or warm blanket may come in handy. You can also bring some items to help you pass the time, such as a book, crossword puzzles, or tablet (don’t forget your charger). Some infusion centers have TVs available, but this can vary. So having your own entertainment can be helpful.

What happens if you miss a dose of Vyepti?

If you miss a dose of Vyepti, contact your healthcare provider to schedule it as soon as possible. If it’s within a few days of when your dose was due, it’s not likely to cause a problem. But if you wait too long between doses, your migraines could return.

After you receive an infusion, it’s a good idea to schedule your next Vyepti dose before you leave the provider’s office. Developing this habit can help keep you on track with your doses. You can also ask your provider’s office if they offer reminder calls. Or you can set a calendar alarm or use a medication reminder app.

How to save on Vyepti

Vyepti is considered a specialty medication. So there may be extra steps required for insurance approval. Since it’s given by a healthcare provider, it may be covered by your medical insurance rather than your pharmacy insurance. Your provider can help you navigate insurance coverage if needed.

GoodRx can help you save on Vyepti, which is only available as a brand-name medication. If you have commercial insurance, you may be eligible to pay as little as $0 per dose using a savings card from the manufacturer. If you’re uninsured or underinsured, a patient assistance program is also available.

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Written by:

Stacia Woodcock, PharmD

Stacia Woodcock, PharmD, is a pharmacy editor for GoodRx. She earned her Doctor of Pharmacy degree from the University of Kentucky and is licensed in New York and Massachusetts.

Reviewed by:

Austin Ulrich, PharmD, BCACP

Austin Ulrich, PharmD, BCACP, is a board-certified ambulatory care clinical pharmacist. In his early career, he provided direct patient care in a variety of settings, including hospital and community pharmacies, and in a primary care clinic as a clinical pharmacist.

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