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Ukoniq

umbralisib
Used for Non-Hodgkin Lymphoma
Used for Non-Hodgkin Lymphoma

Ukoniq (umbralisib) is a medication taken by mouth to treat the blood cancers called marginal zone lymphoma (MZL) and follicular lymphoma (FL). It was approved by the FDA in 2021, but taken off the market shortly after due to safety concerns. It has been discontinued and is no longer available in the United States.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Cydnee Ng, PharmD
Last reviewed on July 24, 2022
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What is Ukoniq (umbralisib)?

What is Ukoniq (umbralisib) used for?

  • Marginal zone lymphoma (MZL)

  • Follicular lymphoma (FL)

How Ukoniq (umbralisib) works

Drug Facts

Common BrandsUkoniq (brand no longer available)
Drug ClassAntineoplastic agent
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Ukoniq (umbralisib)

What is Ukoniq (umbralisib)?
Ukoniq (umbralisib) is an antineoplastic (anticancer) medication used to treat MZL and FL, two types of B-cell lymphomas (cancers that affect white blood cells). In MZL, it's only used in people who've previously received at least one different kind of treatment. In FL, this medication is used for people who've received at least three different kinds of treatments before. In both cases, the previous treatments either didn't work (refractory) or the cancer still came back (relapsed). Ukoniq (umbralisib) is a kinase inhibitor that blocks certain proteins important for cancer cell growth and survival.
Is Ukoniq (umbralisib) still available?
No, Ukoniq (umbralisib) has been discontinued and is no longer available in the United States.
Why was Ukoniq (umbralisib) discontinued?
In 2022, the FDA took away its approval for Ukoniq (umbralisib) due to safety concerns. An ongoing study showed a possible higher risk of death in people receiving this medication.
What should I do if I'm taking Ukoniq (umbralisib)?
If you've been prescribed Ukoniq (umbralisib), work with your provider to find an alternative treatment. You can dispose of Ukoniq (umbralisib) at a drug take-back location, or in your household trash by mixing it with dirt or coffee grounds and sealing the mixture in a plastic bag. Make sure to remove all of your personal information first to protect your privacy.
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alternatives

What are alternatives to Ukoniq (umbralisib)?

There are a number of medications that your doctor can prescribe in place of Ukoniq (umbralisib). Compare a few possible alternatives below.
Ukoniq (umbralisib)
Used for:

  • Marginal zone lymphoma (MZL)

  • Follicular lymphoma (FL)

View Prices
Rituxan (rituximab)
Used for:
View Prices

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