Type your drug name (like Atorvastatin, Sildenafil, etc)
Tuzistra XR
CHLORPHENIRAMINE; CODEINE is a combination of an antihistamine and cough suppressant. It is used to treat the symptoms of cough, allergies, and colds. Compare antihistamine / opioid combinations.
Prescription Settings
ml of oral suspension
120 ml
Tuzistra XR(brand)
ml of oral suspension
120 ml
Coupon Notice: This drug is a controlled substance. Note that some pharmacies may not honor coupons for controlled substances.

Tuzistra XR Side Effects

Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Although serious side effects occur rarely when this medicine is taken as recommended, they may be more likely to occur if: too much medicine is taken, it is taken in large doses, or it is taken for a long period of time.

Get emergency help immediately if any of the following symptoms of overdose occur:

For narcotic antitussive (codeine, dihydrocodeine, hydrocodone, or hydromorphone)-containing

Cold, clammy skin

confusion (severe)

convulsions (seizures)

drowsiness or dizziness (severe)

nervousness or restlessness (severe)

pinpoint pupils of eyes

slow heartbeat

slow or troubled breathing

If you are a nursing mother and you notice any of the following symptoms of overdose in your baby, get emergency help immediately:

Difficulty breathing

difficulty nursing

increased sleepiness (more than usual)


For acetaminophen-containing


increased sweating

loss of appetite

nausea or vomiting

stomach cramps or pain

swelling or tenderness in the upper abdomen or stomach area

For salicylate-containing

Any loss of hearing

bloody urine


convulsions (seizures)

dizziness or lightheadedness

drowsiness (severe)

excitement or nervousness (severe)

fast or deep breathing


hallucinations (seeing, hearing, or feeling things that are not there)

increased sweating

nausea or vomiting (severe or continuing)

shortness of breath or troubled breathing (for salicylamide only)

stomach pain (severe or continuing)

uncontrollable flapping movements of the hands, especially in elderly patients

unusual thirst

vision problems

For decongestant-containing

Fast, pounding, or irregular heartbeat

headache (continuing and severe)

nausea or vomiting (severe)

nervousness or restlessness (severe)

shortness of breath or troubled breathing (severe or continuing)

Check with your doctor as soon as possible if any of the following side effects occur:

For all combinations

Skin rash, hives, and/or itching

For antihistamine- or anticholinergic-containing

Clumsiness or unsteadiness

convulsions (seizures

drowsiness (severe)

dryness of mouth, nose, or throat (severe)

flushing or redness of face

hallucinations (seeing, hearing, or feeling things that are not there)

restlessness (severe)

shortness of breath or troubled breathing

slow or fast heartbeat

For iodine-containing

Headache (continuing)

increased watering of mouth

loss of appetite

metallic taste

skin rash, hives, or redness

sore throat

swelling of face, lips, or eyelids

For acetaminophen-containing

Unexplained sore throat and fever

unusual tiredness or weakness

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


decreased sweating

difficult or painful urination

dizziness or lightheadedness


dryness of mouth, nose, or throat

false sense of well-being

increased sensitivity of skin to sun

nausea or vomiting


stomach pain

thickening of mucus

trouble in sleeping

unusual excitement, nervousness, restlessness, or irritability

unusual tiredness or weakness

Not all of the side effects listed above have been reported for each of these medicines, but they have been reported for at least one of them. There are some similarities among these combination medicines, so many of the above side effects may occur with any of these medicines.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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