provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content

Tri-Chlor

trichloroacetic acid
Used for HPV
Used for HPV

Trichloroacetic acid is a topical gel used to treat genital warts. It's applied by a healthcare provider and can be repeated weekly as needed. The gel can sometimes cause skin irritations and pain. And your provider will make sure to use the smallest amount of this medication to prevent skin problems.

Last reviewed on September 13, 2022
basics-icon

What is Trichloroacetic acid?

What is Trichloroacetic acid used for?

  • Genital warts

  • Anal warts

How Trichloroacetic acid works

Drug Facts

Common BrandsTri-Chlor (brand no longer available)
Drug ClassKeratolytic agent
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
faqs

Frequently asked questions about Trichloroacetic acid

What is trichloroacetic acid and is it still available?
Trichloroacetic acid is a keralytic agent. It works by destroying proteins in the skin cells. This helps to get rid of extra skin cells and eventually causes the wart to disappear. Tri-Chlor, the brand of Trichloroacetic acid, is not available in the United States anymore. But, another form of the gel might still be available. Check with your healthcare provider regarding availabilty of the product.
What is trichloroacetic acid used for?
According to the CDC, trichloroacetic acid is commonly used to treat genital warts and anal warts. Some providers might combine trichloroacetic acid with other medications to help with certain scars, acne, or aging skin. Note that the strength and formulation of trichloroacetic acid are different for these other uses. Talk with your provider about the best option for you.
How is trichloroacetic acid used in genital warts?
Trichloroacetic acid is typically applied to the skin by a healthcare provider. After application, you'll need to wait until the gel dries and appears as a white frost before you can move around. Since treatment only gets rid of the warts and not the virus, you might get genital warts again after treatment, especially in the first few months. As a result, weekly treatment with trichloroacetic acid might be necessary.
What are some side effects of trichloroacetic acid?
Trichloroacetic acid can sometimes cause skin problems after treatment. The risk is higher if too much of the medication is applied onto your skin. Tell your provider right away if you have signs of severe burning, inflammed skin, skin pain, or tenderness after your appointment.
How does trichloroacetic acid compare with imiquimod (Aldara) for genital warts?
Trichloroacetic acid and imiquimod (Aldara) are both topical treatments for genital warts. One main difference between the two medications is how you receive the medication. Trichloroacetic acid is only available at a hospital or clinic, and it's given by a healthcare provider. On the other hand, you can pick up imiquimod (Aldara) at a local pharmacy with a prescription, and use it at home on your own. Another difference is how frequently you receive treatment. Treatment with trichloroacetic acid can be repeated once a week as needed at your provider's office, while imiquimod (Aldara) is applied 1 to 3 times a week for 2 to 4 months. Talk with your provider to determine which treatment is best for you.
Can I use trichloroacetic acid to prevent genital warts?
No. Trichloroacetic acid can only treat genital warts, not prevent them. To lower your risk of genital warts, consider using condoms every time you have sex. You can also receive Gardasil 9 (HPV vaccine) that's available for both males and females to prevent genital warts.
Do I have to tell my sexual partner(s) that I have genital warts?
If you're being treated for genital warts, it's important to let your sexual partner(s) know since the virus that causes the warts (human papillomavirus infection or HPV) can also infect your partner(s). Your provider might also check your partner(s) for genital warts and other STIs.
GoodRxEducationalIcon

How to save using GoodRx

Compare Prices
1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
Select your free coupon
2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
Show coupon to your pharmacist
3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
Get free couponLearn more
alternatives

What are alternatives to Trichloroacetic acid?

There are a number of medications that your doctor can prescribe in place of Trichloroacetic acid. Compare a few possible alternatives below.
Trichloroacetic acid
Used for:
  • Genital warts

  • Anal warts

Used for:
  • Face or scalp actinic keratosis (scaly precancerous spot or growth on the skin) in adults - all brands and strengths

  • Genital and anal warts in adults and children 12 years and older - Zyclara 3.75% and Aldara 5% only

  • Superficial basal cell carcinoma (a type of skin cancer) in adults - Aldara 5% only

$29.86 Lowest GoodRx priceView Prices
Used for:
$32.50 Lowest GoodRx priceView Prices

Get savings updates for Trichloroacetic acid

Receive price alerts, news, and other messages from GoodRx about Trichloroacetic acid and other healthcare topics and relevant savings offers.

By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.