Key takeaways:
Tremfya (guselkumab) is a prescription-only medication that treats Crohn’s disease, plaque psoriasis, psoriatic arthritis, and ulcerative colitis. It’s available as an injection that’s typically self-administered and as an IV infusion given by a healthcare professional.
Tremfya is a brand-name medication and can be costly, with a list price of about $14,000 per injection. Without insurance, a 100 mg/mL One-Press Tremfya injector costs an average of $19238.80.
You can reduce the cost of Tremfya with a manufacturer’s copay savings card (if you have commercial insurance) or through a patient assistance program if you qualify. You may also be able to save by using a GoodRx coupon.
Save on related medications
Crohn’s disease, ulcerative colitis, plaque psoriasis, and psoriatic arthritis are autoimmune conditions. Tremfya (guselkumab) is a brand-name prescription medication that can be used to manage certain types of them all. This biologic treatment is available as a subcutaneous (under-the-skin) injection that’s typically self-administered using the One-Press injector, a prefilled pen, or a prefilled syringe, or given as an IV infusion in a healthcare setting.
Because Tremfya has been found to be effective for several conditions, it is widely prescribed. Here’s how much you can expect to pay and how you may be able to save on this medication.
How much does Tremfya cost?
The list price for Tremfya was $13,873 per dose as of September 2024. This is probably not the price you’ll pay. Tremfya, a specialty medication, is typically administered every 4 to 8 weeks (1 to 2 months). Your cost may be different for an IV treatment in a medical setting.
It’s important to note that Tremfya is a biologic medication, meaning that it’s made using living systems. Biologics don’t have generics. Instead, they have biosimilars, which closely resemble the brand-name (reference) product — but often have a lower cost. No biosimilar for Tremfya is available in the U.S.
Here are some average cash prices for Tremfya:
Tremfya costs
Brand-name form and dose | Average retail price |
One-Press injector, 100 mg/mL | |
Pen (1 pen), 2 mL of 200 mg / 2 mL | |
Prefilled syringe, 100 mg/mL |
Which factors affect the cost of Tremfya?
Without insurance, what you pay for Tremfya depends on several factors, including your:
Pharmacy, since they can set their own prices, and this medication is a specialty drug that you can get only from certain pharmacies
Method of administration, since you can inject Tremfya at home or get an IV infusion in a healthcare setting — which may come with an additional charge
Location, since medication cost can vary based on where you fill your prescription
Dosage, because you may start taking this medication with a higher dose or more frequent injections
Fill quantity, since medications can be more affordable when purchased beyond a monthly supply or at more than 1 dose, for medications given periodically like Tremfya
Does insurance cover Tremfya?
Most health insurance plans cover Tremfya. If you have insurance, review your plan’s summary of benefits and coverage and formulary (list of covered medications) to determine whether Tremfya is covered. If not, contact your plan and ask about your coverage options. You can also discuss alternatives with your prescriber or pharmacist.
For you to get coverage for Tremfya, most health insurance plans require prior authorization, which means your prescriber must provide documentation that Tremfya is medically necessary. And step therapy (when you need to try other medications first) is most common for people covered by Medicaid, commercial plans not purchased through an Affordable Care Act (ACA) marketplace, and ACA plans.
How different insurance plans cover Tremfya
The following charts show the likelihood of having coverage for different self-administration methods of Tremfya with various types of insurance plans. They also show the likelihood of needing to obtain a prior authorization or complete step therapy.
Insurance type | Enrollees covered for Tremfya One-Press injector, 100 mg / 1 mL | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
90.7% | 86.6% | 80% | |
Commercial plans (excluding ACA plans) | 98.7% | 88.1% | 85.5% |
Medicare (original Medicare and Medicare Advantage plans) | 72.3% | 69% | 66.3% |
Medicaid, including state-run and managed care plans | 99.6% | 93.7% | 67.8% |
Source: Managed Markets Insight & Technology, LLC™, as of August 8, 2025 (See methodology below).
Insurance type | Enrollees covered for Tremfya syringe, 100 mg / 1 mL | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
90.7% | 86.6% | 79.9% | |
Commercial plans (excluding ACA plans) | 98.7% | 87.7% | 85.1% |
Medicare (original Medicare and Medicare Advantage plans) | 72.3% | 69% | 65.9% |
Medicaid, including state-run and managed care plans | 99.6% | 93.7% | 67.8% |
Source: Managed Markets Insight & Technology, LLC™, as of August 8, 2025 (See methodology below).
Insurance type | Enrollees covered for Tremfya syringe, 200 mg / 2 mL | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
90.2% | 86.8% | 50.5% | |
Commercial plans (excluding ACA plans) | 98.1% | 87.7% | 59.7% |
Medicare (original Medicare and Medicare Advantage plans) | 71.8% | 68.5% | 32% |
Medicaid, including state-run and managed care plans | 99.5% | 87.7% | 41.3% |
Source: Managed Markets Insight & Technology, LLC™, as of August 8, 2025 (See methodology below).
Best practices for using Tremfya: Tips for getting the most out of this under-the-skin injection, which is usually self-administered every 4 to 8 weeks.
Potential treatments for psoriatic arthritis (PsA): As of early 2025, there are at least 9 medications being studied for PsA treatment. Most are oral pills or under-the-skin injections.
Biologic medications for Crohn’s disease: Why Tremfya and other biologic treatments can make a difference in moderate-to-severe Crohn’s.
Tips if your medication isn’t covered by insurance
If your insurance doesn’t cover Tremfya, you still have options:
Use a GoodRx coupon to save on your prescription.
Ask your prescriber about less costly options that meet your needs. This could mean switching to another brand-name medication that costs less or a medication that has a generic or biosimilar option available. (Tremfya has no biosimilars approved in the U.S.)
Request a formulary exception from your insurance company. If your request is denied, you have the right to file an appeal with your plan.
When it’s time for open enrollment, compare health insurance plans to find one that provides coverage for this medication.
Ways to save on Tremfya
Whether or not you have insurance, there are ways to reduce the cost of Tremfya. Here are four options.
1. Use a GoodRx coupon
You may be able to use a free GoodRx coupon to lower the price of your Tremfya prescription. For example, without insurance, you could pay as low as $14534.63 for a 100 mg/mL One-Press Tremfya injector with a GoodRx coupon at certain pharmacies. Visit www.goodrx.com, or download the GoodRx app on your mobile device and use a coupon. Here’s how:
On the app or website, type “Tremfya” in the search field.
Choose the desired quantity. Input your ZIP code or address, or select “Use my current location,” so you see results for local pharmacies.
Choose how to receive your coupon. You may want it emailed or texted to you, or you may want to print it out.
Take your coupon with you to the pharmacy. Present the coupon to the pharmacy’s staff early in the filling process to help avoid delays at the pickup counter.
It’s worth checking the GoodRx website or app to see if there are available savings on Tremfya at your specialty pharmacy. With a free GoodRx coupon, you could pay the following price for your prescription.
GoodRx prices for Tremfya
Brand-name form and dose | GoodRx price |
One-Press injector, 100 mg/mL | |
Pen (1 pen), 2 mL of 200 mg / 2 mL | |
Prefilled syringe, 100 mg/mL | |
Prefilled syringe, 200 mg / 2 mL |
2. See if you qualify for a copay savings card
Johnson & Johnson, the manufacturer of Tremfya, offers several support solutions to reduce your out-of-pocket costs. If you have commercial insurance, you may be able to benefit from a manufacturer’s copay savings card. You could pay as little as $0 through the Tremfya withMe Savings Program, which can help you pay for out-of-pocket costs toward your copays, coinsurance, and deductible. If you have a Tremfya IV infusion, there’s also support for administration and lab tests with a $2,000 maximum annual benefit. If you’re enrolled in the Tremfya withMe Savings Program, your discount doesn’t get processed or applied at the pharmacy, and you pay out of pocket, you can request a rebate for your out-of-pocket costs. You can add eligible administration and lab test costs to the rebate request if you received a Tremfya infusion.
If your insurance participates in copay adjustment through copay accumulator or copay maximizer programs, you may be subject to savings limits per dose, per month, and annually as a way to ensure the savings accrue to you and not your health plan.
You don’t qualify for the copay savings card if you have government insurance, such as Medicare, Medicaid, or Tricare, or rely on a state patient assistance program or state pharmaceutical assistance program.
You can sign up for financial support by identifying yourself as a patient and choosing the condition you need Tremfya to treat. You’ll be guided to the manufacturer program that best fits your needs. If you have questions, you can call 1-833-948-4631 for assistance.
In addition, a specialty pharmacy often has designated staff members who can help you navigate programs and eligibility.
3. See if you qualify for a patient assistance program
The Johnson & Johnson Patient Assistance Program helps people living in the U.S., including U.S. territories, receive free Tremfya whether you have insurance or not. If you meet income requirements and find your medication unaffordable, you may qualify for this program. Medicare Part D enrollees are eligible if they spend more than 4% of their gross annual household income on prescriptions and show that they are not eligible for the Extra Help low-income subsidy.
You may also be able to get help through other patient assistance programs. If you’re covered by Medicare, the Patient Access Network (PAN) Foundation offers grants to pay treatment costs for people who have a demonstrated need for financial support. The PAN Foundation has an inflammatory bowel disease fund that will help cover copays and other costs for Tremfya. At publication time, this fund was not accepting new or renewal enrollees, but you can join the wait list.
4. Tap into your HSA, FSA, or HRA
Consider using a flexible spending account (FSA), a health savings account (HSA), or a health reimbursement arrangement (HRA) to pay for your medication. You can enjoy multiple tax benefits when funds from an FSA, an HSA, or an HRA are used to pay for qualified healthcare expenses. This can reduce your out-of-pocket costs through tax savings. But be sure to review your account’s contribution limits, rollover limits, and eligible expenses.
The bottom line
Tremfya (guselkumab) is an FDA-approved medication for managing certain types of plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. Without insurance, Tremfya costs about $14,000 per injection. There is no biosimilar version of this medication approved in the U.S.
If you don’t have insurance, the average price of a single 100 mg/mL One-Press Tremfya injector is $19238.80, but you could pay as little as $14534.63 with a GoodRx coupon at select pharmacies.
If you have commercial insurance and use the manufacturer’s copay savings card, your out-of-pocket costs could be as little as $0. If you have no insurance, financial hardship, or Medicare Part D and meet certain income requirements, you may be able to get free medication through the manufacturer’s patient assistance program.
Why trust our experts?
Methodology
We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of August 2025.
We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel.
We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel.
Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel.
These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).
References
Johnson & Johnson Patient Assistance Program. (2025). Quick reference guide.
Lutton, L. (2024). Johnson and Johnson submits FDA request for pediatric Tremfya approval. Managed Healthcare Executive.
PAN Foundation. (n.d.). Inflammatory bowel disease.
PAN Foundation. (n.d.). We’re here to help.
Tremfya withMe. (2025). Commercial or private insurance. Johnson & Johnson.
Tremfya withMe. (2025). Medical benefit rebate form. Johnson & Johnson.
Tremfya withMe. (2025). Paying for Tremfya. Johnson & Johnson.
Tremfya withMe. (2025). Sign up for support today. Johnson & Johnson.
Tremfya withMe. (2025). Tremfya withMe savings program. Johnson & Johnson.
