Is Tekamlo (aliskiren / amlodipine) still available?

No, Tekamlo (aliskiren / amlodipine) has been discontinued and is no longer available.

Why was Tekamlo (aliskiren / amlodipine) discontinued?

It's not completely clear why the manufacturer (Novartis) [discontinued](https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=022545) Tekamlo (aliskiren / amlodipine). But it might've been a precautionary measure related to the FDA's [safety warning](https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-new-warning-and-contraindication-blood-pressure-medicines-containing) for blood pressure medications containing aliskiren with [ACE inhibitors](https://www.goodrx.com/classes/ace-inhibitors) (e.g., [lisinopril (Prinivil)](https://www.goodrx.com/lisinopril/what-is)) and [ARBs](https://www.goodrx.com/classes/arbs) (e.g., [losartan (Cozaar)](https://www.goodrx.com/losartan/what-is), [valsartan (Diovan)](https://www.goodrx.com/valsartan/what-is)). This safety warning came from a study that showed a higher risk of kidney problems, high potassium levels, and low blood pressure in certain people taking aliskiren along with an ACE inhibitor or ARB to treat high blood pressure compared to people taking an ACE inhibitor or ARB alone. This study led Novartis to discontinue their aliskiren-containing combination medication [Valturna (aliskiren / valsartan)](https://www.goodrx.com/valturna/what-is).

Tekamlo

Q: What is Tekamlo (aliskiren / amlodipine)?

Tekamlo (aliskiren / amlodipine) is a combination of two medications that work together to treat high blood pressure. __Aliskiren__ is a direct renin inhibitor –– it blocks a substance in your body called renin that normally causes your blood vessels to tighten and raise your blood pressure. __Amlodipine__ is a calcium channel blocker that works to relax your blood vessels, resulting in lower blood pressure.

aliskiren / amlodipine

Used for Hypertension

Tekamlo (aliskiren / amlodipine) is a combination medication used to treat high blood pressure. It contains two medications that work to lower your blood pressure by relaxing your blood vessels. Tekamlo (aliskiren / amlodipine) is no longer available because it has been discontinued.

Reviewed by:

Kristianne Hannemann, PharmD

Cydnee Ng, PharmD

Last reviewed on December 13, 2021

What is Tekamlo (aliskiren / amlodipine)?

Drug facts

Common BrandsTekamlo(brand no longer available)

Drug ClassDirect renin inhibitor / Calcium channel blocker

Controlled Substance ClassificationNot a controlled medication

Generic StatusNo lower-cost generic available

AvailabilityDiscontinued

Common questions about Tekamlo

Tekamlo is a combination of two medications that work together to treat high blood pressure. Aliskiren is a direct renin inhibitor –– it blocks a substance in your body called renin that normally causes your blood vessels to tighten and raise your blood pressure. Amlodipine is a calcium channel blocker that works to relax your blood vessels, resulting in lower blood pressure.

No, Tekamlo has been discontinued and is no longer available.

It's not completely clear why the manufacturer (Novartis) discontinued Tekamlo. But it might've been a precautionary measure related to the FDA's safety warning for blood pressure medications containing aliskiren with ACE inhibitors (e.g., lisinopril (Prinivil)) and ARBs (e.g., losartan (Cozaar), valsartan (Diovan)). This safety warning came from a study that showed a higher risk of kidney problems, high potassium levels, and low blood pressure in certain people taking aliskiren along with an ACE inhibitor or ARB to treat high blood pressure compared to people taking an ACE inhibitor or ARB alone. This study led Novartis to discontinue their aliskiren-containing combination medication Valturna (aliskiren / valsartan).

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Tekamlo (aliskiren / amlodipine) dosage

Typical dosage for Tekamlo (aliskiren / amlodipine)

Interactions between Tekamlo (aliskiren / amlodipine) and other drugs

Tekamlo (aliskiren / amlodipine) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Tekamlo (aliskiren / amlodipine). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Abametapir
Atazanavir
Capmatinib
Ceritinib
Clarithromycin
Clopidogrel
Conivaptan
Cyclosporine
Dantrolene
Digoxin
Domperidone
Droperidol
Epirubicin
Fosnetupitant
Itraconazole
Lacosamide
Lasmiditan
Netupitant
Piperaquine
Rifampin
Ritonavir
Simeprevir
Simvastatin
Tacrolimus
Tegafur
Telaprevir
Venetoclax

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.