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Targiniq ER
Targiniq ER (oxycodone / naloxone) is a combination medication used to treat pain when non-opioid medications don't provide enough relief. It's no longer available in the United States, because it was discontinued.
Last reviewed on July 13, 2022
What is Targiniq ER (oxycodone / naloxone)?
What is Targiniq ER (oxycodone / naloxone) used for?
Pain that isn't relieved by non-opioid medications
How Targiniq ER (oxycodone / naloxone) works
Drug Facts
Common BrandsTarginiq ER (brand no longer available)
Drug ClassOpioid agonist / Opioid antagonist
Controlled Substance ClassificationSchedule II
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
Frequently asked questions about Targiniq ER (oxycodone / naloxone)
What is Targiniq ER (oxycodone / naloxone)?
Targiniq ER (oxycodone / naloxone) is made up of two medications. Oxycodone is an opioid medication that binds (attaches) to mu-opioid receptors in your brain to lower your response to pain. Naloxone is an opioid antagonist that blocks opioid receptors in your brain. The naloxone component is used to help prevent medication abuse. It blocks the pleasurable effects that occur when people abuse the medication through means other than swallowing it whole (e.g., self-injection, crushed tablet), but also causes bothersome effects when this is done.
Is Targiniq ER (oxycodone / naloxone) still available?
No, Targiniq ER (oxycodone / naloxone) has been discontinued and is no longer available in the United States. It's not clear why this medication has been discontinued.
What are other ways to lower pain in place of Targiniq ER (oxycodone / naloxone)?
There are some non-medication options to help with pain. These alternatives include physical therapy, massage, and cognitive behavioral therapy (CBT). Ask your provider about non-medication options or other pain medications that might be right for you.
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