The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low platelet count (up to 76%)
- Low red blood cell count (anemia; up to 61%)
- Infection (up to 56%)
- Low white blood cell count (up to 53%)
- Diarrhea (up to 41%)
- Nausea (up to 35%)
- Injection-site reaction (up to 35%)
- Lack of energy (up to 31%)
- Fever (up to 29%)
- Stomach pain (up to 23%)
- Fever with low white blood cell count (febrile neutropenia; up to 20%)
- Headache (up to 20%)
Less Common Side Effects
- Vomiting
- Constipation
- Loss of appetite
- Nose bleeds
- Cough
- Difficulty breathing
- Hair loss
- Trouble sleeping
- Chills
- Rash
- Swelling in arms and legs
- Pain in arms, legs, back, joints, or muscles
Synribo serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious infections: repeated fevers, chills, sweating, trouble breathing
- Serious bleeding: unusual bleeding, easy bruising, blood in urine or stool, confusion, vision changes
Source: DailyMed
The following Synribo side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Black, tarry stools
bleeding gums
bloating or swelling of the face, arms, hands, lower legs, or feet
blood in the urine or stools
bloody nose
chills
lower back or side pain
painful or difficult urination
pale skin
pinpoint red spots on the skin
rapid weight gain
tingling of the hands or feet
troubled breathing with exertion
ulcers, sores, or white spots in the mouth
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight gain or loss
Incidence not known
Arm, back, or jaw pain
blurred vision
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain or discomfort
confusion
convulsions
decreased urination
deep, dark purple bruises
difficulty with speaking
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
double vision
fainting
fast, shallow breathing
fast, slow, pounding, or irregular heartbeat or pulse
flushed, dry skin
fruit-like breath odor
headache
hives, rash, or itching, pain, redness, or swelling of the skin
hoarseness
inability to move the arms, legs, or facial muscles
inability to speak
increased hunger
increased thirst
increased urination
irritation
joint pain, stiffness, or swelling
loss of consciousness
muscle cramps
nervousness
pale, clammy skin
pounding in the ears
rapid breathing
slow speech
stomachache
sunken eyes
sweating
swelling of the eyelids, face, lips, hands, or feet
thirst
troubled breathing or swallowing
unexplained weight loss
vomiting of blood or material that looks like coffee grounds
wrinkled skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Abdominal or stomach pain
back pain
bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
difficulty having a bowel movement (stool)
difficulty with moving
hair loss or thinning of the hair
lack or loss of strength
loss of appetite
muscle pain or stiffness
pain in the arms or legs
trouble sleeping
upper abdominal or stomach pain
Incidence not known
Acid or sour stomach
belching
bleeding gums
bloody eye
bone pain
burning, dry, or itching eyes
continuous ringing or buzzing or other unexplained noise in the ears
darkening of the skin
decreased appetite
double vision
ear pain
eye discharge or excessive tearing
general feeling of discomfort or illness
hearing loss
increased sweating
indigestion
itching skin
muscle spasm, stiffness, or weakness
redness and swelling of the gums
redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
stomach discomfort or upset
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
