stavudine

Generic Zerit

Used for HIV Treatment

Basics FAQs Dosage Interactions Latest news Prices Medicare

Stavudine was one of the first HIV antiretroviral (ARV) medications approved by the FDA. It has a lot of serious side effects that have limited its use in recent years and is no longer available in the U.S.

Reviewed by:

Hope Chang, PharmD, AAHIVP

Michelle Nguyen, PharmD

Last reviewed on May 31, 2021

Basics FAQs Dosage Interactions Latest news Prices Medicare

What is Stavudine?

Drug facts

Common BrandsZerit(brand no longer available)

Drug ClassHIV ARV

Controlled Substance ClassificationNot a controlled medication

Generic StatusNo lower-cost generic available

AvailabilityDiscontinued

Common questions about Stavudine

Stavudine is an antiretroviral (ARV) medication that stops the HIV virus from infecting your cells. It's in a subclass called "NRTI," similar to HIV ARVs like Viread and Epivir, which are commonly used.

No, there are no brand or generic versions available in the U.S.

It's likely that the manufacturer decided to stop making stavudine due to a lack of demand. Stavudine can cause a lot of serious side effects and can't be taken with certain HIV ARVs.

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Stavudine dosage

Typical dosage for Stavudine

Interactions between Stavudine and other drugs

Stavudine may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Stavudine. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Didanosine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Cabotegravir
Doxorubicin
Doxorubicin Hydrochloride Liposome
Hydroxyurea
Orlistat
Pexidartinib
Ribavirin
Zidovudine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.