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Simulect

basiliximab
Used for Organ Transplant

Simulect (basiliximab) is an infusion given in the hospital, typically shortly before and after a kidney transplant to prevent your body from rejecting the new organ. It's given in combination with other medications, such as cyclosporine (Neoral) and corticosteroids, to prevent transplant injection. The most common side effects Simulect (basiliximab) can cause are stomach-related, including stomach pain, nausea, and vomiting. And just like other medications that are taken to prevent organ rejection, Simulect (basiliximab) can raise your risk of infections.

Reviewed by:Last reviewed on January 30, 2023
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What is Simulect (basiliximab)?

What is Simulect (basiliximab) used for?

  • Prevention of kidney transplant rejection

Drug facts

Common BrandsSimulect
Drug ClassMonoclonal antibody
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Simulect (basiliximab) dosage

Typical dosage for Simulect (basiliximab)

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Interactions between Simulect (basiliximab) and other drugs

Simulect (basiliximab) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Simulect (basiliximab). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Echinacea
  • Tofacitinib

References

Best studies we found

Brennan, D. C., et al. (2006). Rabbit antithymocyte globulin versus basiliximab in renal transplantation. The New England Journal of Medicine.

Claeys, E., et al. (2019). Immunosuppressive drugs in organ transplantation to prevent allograft rejection: Mode of action and side effects. Journal of Immunological Sciences.

Kirk, A. D. (2006). Induction immunosuppression. Transplantation.

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