Serotonin antagonists are used to treat irritable bowel syndrome (IBS) and nausea. They work by reducing cramps, discomfort, and diarrhea.

Why are
Serotonin Antagonists
prescribed?

How is this chart calculated?

How we make this chart

This chart is created by aggregating the total number of claims for the drugs in this class divided by the # of drugs with a specific indication. It is meant to be representative but may not accurately reflect the actual # of prescriptions written to treat a specific condition.

Prices for Popular Serotonin Antagonists

Popularity Brand Name (Generic Name) GoodRx Fair Price Price Trend
Zofran
(ondansetron)
13
See Prices
Ondansetron (Zofran) is a moderately priced drug used to treat nausea and vomiting caused by chemotherapy. It is also used to prevent or treat nausea and vomiting after surgery. This drug is more popular than comparable drugs. It is available in brand and generic form. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
Lotronex
(alosetron)
714
See Prices
ALOSETRON is used to treat irritable bowel syndrome (IBS) in women. It is reserved for those women who have severe diarrhea as the main symptom and who have not had success with other treatments. This medicine has not been shown to work in men with IBS.
granisetron
253
See Prices
GRANISETRON is used to prevent nausea and vomiting caused by chemotherapy or radiation therapy.
Sancuso
2,006
See Prices
GRANISETRON is an antiemetic. It is used to prevent nausea and vomiting caused by chemotherapy.
Aloxi
5,553
See Prices
PALONOSETRON is used to prevent nausea and vomiting caused by chemotherapy. It also helps prevent delayed nausea and vomiting that may occur a few days after your treatment.
Granisol
79
See Prices
Anzemet
106
See Prices
Xermelo
N/A N/A See Prices
Xermelo is an expensive drug used to treat carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy. This drug is indicated for adults inadequately controlled by SSA therapy. There are currently no generic alternatives for Xermelo. It is not covered by most medicare and insurance plans, but manufacture and pharmacy coupons can help offset the cost.
Zuplenz
109
See Prices
ONDANSETRON is used to treat nausea and vomiting caused by chemotherapy. It is also used to prevent or treat nausea and vomiting after surgery.

Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Recent News

Copyright ©2017 GoodRx, Inc.

GoodRx is not sponsored by or affiliated with any of the pharmacies identified in its price comparisons. All trademarks, brands, logos and copyright images are property of their respective owners and rights holders and are used solely to represent the products of these rights holders. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment.

In all states except Tennessee, GoodRx is considered a marketer of prescription discount cards, and is not required to register as a discount card provider. In Tennessee, GoodRx is registered as a Prescription Drug Discount Plan Operator.