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Ser-Ap-Es
Ser-Ap-Es is a combination medication containing hydralazine, hydrochlorothiazide, and reserpine. The medication is used to lower blood pressure. It's no longer available in the United States because it was discontinued.
Last reviewed on June 27, 2022
What is Ser-Ap-Es ?
What is Ser-Ap-Es used for?
High blood pressure
How Ser-Ap-Es works
Drug Facts
Common BrandsSer-Ap-Es (brand no longer available)
Drug ClassVasodilator / Diuretic / Rauwolfia alkaloid
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
Frequently asked questions about Ser-Ap-Es
What is Ser-Ap-Es ?
Ser-Ap-Es is made up of three medications that all lower your blood pressure. Hydralazine is a vasodilator that relaxes blood vessels, causing them to open up (dilate). Hydrochlorothiazide (Microzide) (HCTZ), is a thiazide diuretic (water pill) that works in the kidneys to remove extra water, which lowers blood pressure and gets rid of swelling. Reserpine is a Rauwolfia alkaloid that works by lowering the levels of certain chemicals in your body that can raise your blood pressure.
Is Ser-Ap-Es still available?
No, Ser-Ap-Es has been discontinued and is no longer available in the United States. Although it's not exactly clear why Ser-Ap-Es has been discontinued, it's probably because newer medications are available.
What are examples of currently available medications that are used in place of Ser-Ap-Es ?
While reserpine as a single-ingredient medication has also been discontinued, both hydralazine and hydrochlorothiazide (Microzide) are still available today on their own as well as part of a combination of other medications. There are also many available medications commonly used today for the treatment of high blood pressure.
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What are alternatives to Ser-Ap-Es ?
There are a number of medications that your doctor can prescribe in place of Ser-Ap-Es . Compare a few possible alternatives below.
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