Lidocaine 4% patch (Salonpas) is an over-the-counter (OTC) medication used to relieve minor muscles and joint pain in adults and children 12 years and older. It's often used for temporary relief of backaches, arthritis, strains and sprains, and bruises. The patch is a local anesthetic that numbs the area where it's applied. You place the patch directly on the skin and can use it 3 to 4 times a day, leaving it on for up to 8 hours at a time. Common side effects include mild skin irritation or redness where the patch is applied.
Temporary relief of minor pain due to:
Lidocaine 4% patch (Salonpas) is a local anesthetic, which means it works by numbing the area where it’s applied. It blocks pain signals from the nerves in your skin so they don’t reach your brain. This helps relieve pain in a specific spot without affecting the rest of your body.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Available over the counter
Generally well-tolerated with few side effects
Can use up to 3 to 4 times a day
Can only use 1 patch at a time
Commonly causes skin irritation, rash, itchiness, and redness
Not recommended for use in children under 12 years old
Always wash your hands after applying lidocaine 4% patch (Salonpas). This removes any medication that might have gotten on your fingers. Don’t touch your eyes before washing your hands since lidocaine can cause painful burning or irritation if it gets in your eyes.
Apply lidocaine 4% patch (Salonpas) only to clean, dry, and healthy skin. Don’t use it on cuts, scrapes, or broken skin.
Don't use heat sources over lidocaine 4% patch (Salonpas), like heating pads or electric blankets. Heat can make your body absorb too much lidocaine, which can cause serious side effects.
Avoid using other products with lidocaine (like prescription patches or creams, ointments, and gels) while using lidocaine 4% patch (Salonpas) at the same time. Using multiple lidocaine products together can raise your risk of side effects. Talk to your pharmacist if you’re unsure what contains lidocaine.
Stop using lidocaine 4% patch (Salonpas) and talk with a healthcare professional if you’ve used it for more than a week or if symptoms come back after they’ve gone away. Also let them know if you have rash, itching, redness, irritation, swelling, or blistering where you applied the patch.
Throw away each lidocaine 4% patch (Salonpas) after one use. Fold it in half with the sticky sides together before tossing it. This helps prevent kids or pets from touching or chewing on the used patch, which could still contain medication.
Store lidocaine 4% patch (Salonpas) safely out of children’s reach and sight. This keeps them from accidentally chewing or touching the patch. If you think a child might have had contact with a patch, call Poison Control at 1-800-222-1222 right away, even if you’re not sure.
Lidocaine 4% patch (Salonpas) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
*Risk factors: History of methemoglobinemia | History of low glucose-6-phosphate dehydrogenase (G6PD) | Heart or lung problems | Age 6 months or younger | Exposure to other oxidizing agents, such as chlorine and hydrogen peroxide | Taking other medications that raise the risk for methemoglobinemia *
While rare, local anesthetics like lidocaine 4% patch (Salonpas) can cause methemoglobinemia, a serious blood problem where your red blood cells can't carry enough oxygen throughout your body. The risk is higher in people with glucose-6-phosphate dehydrogenase (G6PD) deficiency, a history of methemoglobinemia, heart or lung problems, and in infants under 6 months. Be careful using lidocaine 4% patch (Salonpas) patches if you're around oxidizing chemicals like chlorine or hydrogen peroxide, which might be present in cleaning supplies or hair dye.
Symptoms can show up right away or a few hours later, and can include gray, blue, or pale-colored skin. If not treated quickly, methemoglobinemia can lead to seizures, irregular heartbeat, coma, or even death. If you notice any of these symptoms, stop using lidocaine 4% patch (Salonpas) and get emergency medical help right away.
Risk factors: Using heating pad or electric blanket on skin | Applying the patch to red, irritated, or broken skin | Leaving the patch on for more than 12 hours | Using more patches than recommended | Liver problems | Kidney problems
Your body can absorb too much lidocaine from lidocaine 4% patch (Salonpas) if you use more patches than recommended or leave them on too long. This can also happen if you put the patches on broken skin or use a heating pad over them. Absorbing too much lidocaine is dangerous and can cause serious side effects. If you notice numbness around your mouth, tingling in your tongue, dizziness, ringing in your ears, or blurred vision, remove the patch and get medical help immediately.
Risk factors: Not storing or throwing away lidocaine 4% patch (Salonpas) patches correctly
When you’re done using a lidocaine 4% patch (Salonpas), fold it in half with the sticky sides together before throwing it away. This helps keep the medication from getting on a child or pet if they find it. Even a used patch can still contain a lot of lidocaine, and if a child or pet chews or swallows it, it could cause serious harm. Always store and throw the patches away safely and out of reach. If you think a child or pet has chewed or eaten a patch, call 911 or Poison Control at 1-800-222-1222 right away.
Adults and children ages 12 years and older: The typical dose is to apply 1 patch to the affected area of skin, no more than 3 to 4 times a day for up to 8 hours each time. Check the directions on the box for specific instructions.
Children under 12 years old: Ask your child's pediatrician.
Temporary relief of minor pain due to:
Arthritis
Backache
Strains
Sprains
Bruises
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Hisamitsu Pharmaceutical Co., Inc. (2025). Salonpas Lidocaine Pain Relieving- lidocaine patch [package insert]. DailyMed.
MedlinePlus. (2017). Sprains and strains.
MedlinePlus. (2023). Glucose-6-phosphate dehydrogenase deficiency.
MedlinePlus. (2023). Pain medications - narcotics.
MedlinePlus. (2024). Methemoglobinemia.
MotherToBaby. (2023). Lidocaine. Organization of Teratology Information Specialists.
Torp, K. D., et al. (2022). Lidocaine toxicity. StatPearls.
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