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Rezira

hydrocodone / pseudoephedrine
Used for Nasal Congestion, Cold Symptoms, Cough
Used for Nasal Congestion, Cold Symptoms, Cough

Rezira (hydrocodone / pseudoephedrine) is a combination medication used to treat cough and stuffy nose. It shouldn't be used in children under the age of 18 because of the risk of overdose. It should be used with caution in adults because of the risk of serious breathing problems. This medication is no longer available on the market.

Reviewed by:
reviewer
Shifali Patel, PharmD
reviewer
Michelle Nguyen, PharmD
Last reviewed on January 9, 2022
BasicsFAQsInteractionsLatest newsPricesMedicare
Rezira (hydrocodone / pseudoephedrine) is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.
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What is Rezira (hydrocodone / pseudoephedrine)?

How Rezira (hydrocodone / pseudoephedrine) works

Are you looking for information on Zutripro (hydrocodone / chlorpheniramine / pseudoephedrine) or Tussionex (hydrocodone / chlorpheniramine) instead?

Drug Facts

Common BrandsRezira (brand no longer available)
Drug ClassOpioid / Decongestant
Controlled Substance ClassificationSchedule II
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Rezira (hydrocodone / pseudoephedrine)

What is Rezira (hydrocodone / pseudoephedrine)?
Rezira (hydrocodone / pseudoephedrine) is a combination medication used to treat symptoms of a common cold, such as cough and stuffy nose. Hydrocodone is an opioid that works on the cough center in your brain to prevent coughing. Pseudoephedrine (Sudafed) is a decongestant that relieves stuffiness in your nose. Rezira (hydrocodone / pseudoephedrine) should be used carefully because it can become habit-forming and lead to life-threatening breathing problems and overdose, especially when combined with alcohol.
Is Rezira (hydrocodone / pseudoephedrine) still available?
No. Rezira (hydrocodone / pseudoephedrine) is no longer available as a brand or generic medication in the United States.
Why was Rezira (hydrocodone / pseudoephedrine) discontinued?
It's unknown why Rezira (hydrocodone / pseudoephedrine) was discontinued. According to the U.S. Food and Drug Administration (FDA), Rezira (hydrocodone / pseudoephedrine) wasn't discontinued because it was unsafe or didn't work well. It's possible that it was removed from the market due to the availability of other medications to treat cough and stuffy nose.
What can I take to replace Rezira (hydrocodone / pseudoephedrine)?
If you used Rezira (hydrocodone / pseudoephedrine) in the past or if you currently have a cough or stuffy nose, discuss other options with your healthcare provider. Depending on the nature of your symptoms and your medical history, your provider will help guide you to a medication that's best for you.
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interactions

Interactions between Rezira (hydrocodone / pseudoephedrine) and other drugs

Rezira (hydrocodone / pseudoephedrine) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Rezira (hydrocodone / pseudoephedrine). Please note that only the generic name of each medication is listed below.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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