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Restora

lactobacillus casei / omega-3 fatty acids
Used for Nutritional Deficiency
Used for Nutritional Deficiency

Restora is a combination product containing omega-3 fish oil and a probiotic (lactobacillus) taken by mouth as a dietary supplement. It's used to help support gut health in people over the age of 12 years old. You only need to take Restora once a day, and it's available as capsules that are found over the counter (OTC). Side effects aren't common with this product.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Allison Gourley, PharmD
Last reviewed on July 2, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostAlternativesReferencesPricesMedicare
basics-icon

What is Restora?

What is Restora used for?

How Restora works

Restora is a combination of two different dietary supplements:

  • Lactobacillus casei (or probiotic KE-99) is a particular species of "good" bacteria that might offer many health benefits, including supporting your gut health.

  • Omega-3 fatty acids are fats that have many functions in our bodies, like building and supporting cells. The manufacturer of Restora claims omega-3 fish oil can help the probiotic in this product work better.

Are you looking for information on Restora RX (folic acid / lactobacillus casei) instead?

Drug Facts

Common BrandsRestora
Drug ClassDietary supplement
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityOver-the-counter
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Avg retail price
$56.02(save 35.63%)
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$36.06
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What are the side effects of Restora?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

See Risks and Warnings.

Source: DailyMed

pros-and-cons

Pros and cons of Restora

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Pros

Only need to take one capsules a day

Can be kept at room temperature

Available over the counter

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Cons

Can't use in children younger than 12 years old

Contains fish, shellfish, and soy, so not a good choice for people with these allergies

No lower-cost generic available

pharmacist-tips

Pharmacist tips for Restora

pharmacist

  • Keep Restora at or below room temperature, between 59 and 86 degrees Fahrenheit. Make sure to protect the capsules from heat, humidity, or direct sunlight, since this could damage the medication.

    • Take Restora between meals, unless directed differently by your healthcare professional (HCP).

      • It's not known if Restora can harm an unborn baby or infant, so talk to your OB-GYN provider before starting this product if you're pregnant, planning to become pregnant, or breastfeeding.

        faqs

        Frequently asked questions about Restora

        Can Restora raise blood sugar levels?
        While some studies suggest that omega-3 fish oils (an ingredient in Restora) might raise blood sugar levels in people with diabetes, other studies do not support this. On the other hand, lactobacillus, another ingredient in Restora, has shown potential in lowering blood sugar. If you have diabetes and notice changes in your blood sugar after starting Restora, discuss this with your healthcare professional (HCP).
        How fast does Restora work?
        It's difficult to say since it's different for everyone. If you've been taking Restora consistently as directed and you're still experiencing constipation, diarrhea, gas, and bloating, speak with your HCP about other options to help your symptoms.
        Can Restora help with occasional digestive problems?
        Maybe. Probiotics like Restora can help protect your gut health. Because of this, they have many potential benefits related to gut health like constipation, gas, bloating, and diarrhea. But more research is needed to confirm that probiotics can greatly help improve these digestive problems.
        Is Restora the same as Restora RX?
        Although both Restora and Restora RX work to help support your gut health, they're different medications. Restora RX contains folic acid and lactobacillus, and it's only available with a prescription. Restora contains fish oil and lactobacillus, and it's available to purchase over the counter. Additionally, Restora RX capsules contain a higher amount of lactobacillus (60 mg) compared to Restora (45 mg). Speak with your HCP to see which medication is best for you.
        Can I take Restora if I have a weak immune system?
        If you have a weakened immune system, speak with your healthcare team before taking Restora to make sure it's safe for you. People with a weakened immune system have a higher risk of harmful effects, such as getting infections, when taking medications with live bacteria.
        Can I take Restora with my antibiotics?
        Probiotics like Restora might be able to improve stomach-related side effects like diarrhea that might happen when you take antibiotics. Probiotics might help replace the gut bacteria that's lost from the use of antibiotics and restore your gut health. If you've been prescribed an antibiotic, discuss with your HCP to see if you should also take a probiotic.
        Does Restora have a fishy smell or taste?
        The manufacturer claims that Restora doesn't smell or taste like anything. If your capsules have a strange taste or smell, this might mean they aren't good anymore, and you might have to throw them away.
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        What are the risks and warnings for Restora?

        Restora can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

        risk-warning

        Risk of bleeding

        • Risk factors: Taking anticoagulants (blood-thinning medications)

          Restora contains omega-3 fatty acids. Taking more than 3 grams of omega-3 fatty acids per day might raise your risk for bleeding problems. Let your healthcare professional (HCP) know if you're taking blood thinners, like warfarin (Coumadin), or other products that contain omega-3 fatty acids before starting Restora.

          dosage

          Restora dosage forms

          The average cost for 1 carton of 30 capsules of 400mg/120mg/64mg of Restora is $36.06 with a free GoodRx coupon. This is 35.63% off the average retail price of $56.02.
          carton
          Carton
          DosageQuantityPrice as low asPrice per unit
          30 capsules of 400mg/120mg/64mg1 carton$36.06$36.06

          Typical dosing for Restora

          Each capsule contains 45 mg of Lactobacillus casei and 400 mg of omega-3 fish oil.

          Adults and children 12 years and older: The typical dose is 1 capsule by mouth once a day, or as prescribed by your healthcare professional (HCP).

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          How much does Restora cost?

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          Restora (brand)
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          alternatives

          What are alternatives to Restora?

          There are a number of medications that your doctor can prescribe in place of Restora. Compare a few possible alternatives below.
          Restora
          Used for:
          $36.06 Lowest GoodRx priceView Prices
          Restora Rx
          Used for:
          $49.64 Lowest GoodRx priceView Prices

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          References

          Best studies we found

          Friday, K. E., et al. (1989). Elevated plasma glucose and lowered triglyceride levels from omega-3 fatty acid supplementation in type II diabetes. Diabetes Care.

          Gao, C., et al. (2020). Effects of fish oil supplementation on glucose control and lipid levels among patients with type 2 diabetes mellitus: A meta-analysis of randomized controlled trials. Lipids in Health and Disease.

          Hempel, S., et al. (2012). Probiotics for the prevention and treatment of antibiotic-associated diarrhea: A systematic review and meta-analysis. Journal of the American Medical Association.

          View All References (6)

          Hill, D., et al. (2018). The Lactobacillus casei group: History and health related applications. Frontiers in Microbiology.

          Khalili, L., et al. (2019). The effects of Lactobacillus casei on glycemic response, serum sirtuin1 and fetuin-a levels in patients with type 2 diabetes mellitus: A randomized controlled trial. Iranian Biomedical Journal.

          Kris-Etherton, P. M., et al. (2003). Omega-3 fatty acids and cardiovascular disease: New recommendations from the American Heart Association. Arteriosclerosis, Thrombosis, and Vascular Biology.

          National Centers for Complementary and Integrative Health. (2019). Probiotics: Usefulness and safety.

          U.S. Pharmaceutical Corporation. (2022). Restora- lactobacillus casei ke-99 enhanced with omega-3 capsule [package insert]. DailyMed.

          US Pharmaceuticals Corporation. (n.d.). Restore your flora with Restoraâ„¢.

          GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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