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Renagel Coupon - Renagel 800mg tablet
SEVELAMER is a polymer. It binds phosphates in the stomach and prevents them from being absorbed into the body. This medicine is used in patients with chronic kidney disease on dialysis to prevent dangerous increases in phosphates. Compare phosphate binders.
Renagel Coupon - Renagel 800mg tablet
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What is Renagel?

Commonly Used Brand Name(s)Renagel, Renvela

Therapeutic ClassificationsPhosphate Binder

Pharmacologic ClassificationsBile Acid Sequestrant

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OverviewTOP

Sevelamer is used to treat hyperphosphatemia (too much phosphate in the blood) in patients with chronic kidney disease who are on dialysis.

This medicine is available only with your doctor's prescription.

Proper UseTOP

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Take this medicine with meals.

Follow carefully any diet program your doctor may recommend.

How to use the powder for oral suspension:

  • Pour the entire contents of the packet in an empty cup.
  • Mix the powder with 2 tablespoons of water for the 0.8 gram dose or 4 tablespoons of water for the 2.4 gram dose.
  • Stir the mixture vigorously and drink it as soon as you can or within 30 minutes. Be sure to stir the mixture again before drinking if you decide to wait.

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

If you are taking any other medicines, you may be asked to take them at least 1 hour before or 3 hours after you take sevelamer. If you need help deciding the best times to take your other medicines, ask your doctor or pharmacist.

DosingTOP

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For high phosphorus levels in the blood:
    • For oral dosage forms (suspension or tablets):
      • For patients not taking a phosphate binder:
        • Renagel®:
          • Adults—At first, 800 to 1600 milligrams (mg) three times a day with meals, depending on your blood phosphorus level. Your doctor will adjust your dose as needed.
          • Children—Use and dose must be determined by your doctor.
        • Renvela®:
          • Adults—At first, 800 to 1600 mg (1 to 2 tablets) or 0.8 to 1.6 grams (g) of powder for suspension three times a day with meals depending on your blood phosphorus level. Your doctor will adjust your dose as needed.
          • Children—Use and dose must be determined by your doctor.
      • For patients switching from Renagel® tablets to Renvela® powder for suspension or tablets:
        • Adults—Use the same dose in grams. Your doctor will adjust your dose as needed.
        • Children—Use and dose must be determined by your doctor.
      • For patients switching from calcium acetate to sevelamer, your doctor will determine the best dose for you and adjust as needed.

Missed DoseTOP

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Use & StorageTOP

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Before UsingTOP

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

AllergiesTOP

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

PediatricTOP

Appropriate studies have not been performed on the relationship of age to the effects of sevelamer in the pediatric population. Safety and efficacy have not been established.

GeriatricTOP

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sevelamer in the elderly. However, elderly patients may start at a lower dose.

PregnancyTOP

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast FeedingTOP

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Drug InteractionsTOP

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Other InteractionsTOP

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical ProblemsTOP

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bowel blockage—Should not be used in patients with this condition.
  • Difficulty with swallowing or other swallowing problems or
  • Major surgery on the gastrointestinal tract or
  • Stomach or bowel problems (e.g., constipation), severe—Use with caution. May cause serious side effects if the tablet cannot be swallowed completely and properly absorbed.

PrecautionsTOP

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

If your symptoms do not improve or if they get worse, call your doctor.

Many people with kidney problems need to be on a special diet. To keep your kidney disease from getting worse, it is very important that you follow your special diet and take your medicines regularly, even if you are feeling better.

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