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Quinapril Coupon - Quinapril 40mg tablet

quinapril

Generic Accupril
Used for Heart Failure, Hypertension
Used for Heart Failure, Hypertension

Quinapril (also known by its brand name, Accupril) is an angiotensin-converting enzyme (ACE) inhibitor. It's used to treat high blood pressure and heart failure in adults. This medication is available as a lower-cost generic tablet that's taken by mouth once or twice per day. Side effects include headache, dizziness, and cough.

Last reviewed on October 26, 2023
basics-icon

What is Quinapril (Accupril)?

What is Quinapril (Accupril) used for?

  • High blood pressure

  • Heart failure

How Quinapril (Accupril) works

Quinapril (Accupril) is an angiotensin-converting enzyme (ACE) inhibitor. ACE is a protein in your body that works to squeeze your blood vessels and help your blood pressure go up. Quinapril (Accupril) blocks how ACE works, which causes your blood vessels to relax. This helps lower your blood pressure.

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Drug Facts

Common BrandsAccupril
Drug ClassACE inhibitor
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Quinapril (Accupril) essentials

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What are the side effects of Quinapril (Accupril)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

High blood pressure:
  • Headache (6%)
  • Dizziness (4%)
  • Fatigue (3%)
Heart failure:
  • Dizziness (8%)
  • Cough (4%)
  • Fatigue (3%)
  • Low blood pressure (3%)

Other Side Effects

High blood pressure:
  • Cough
  • Nausea or vomiting
  • Stomach pain
Heart failure:
  • Shortness of breath
  • Nausea or vomiting
  • Diarrhea
  • Headache
  • Chest pain
  • Muscle or back pain
  • Rash

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Angioedema (severe swelling): swelling (in the face, arms or legs, lips, tongue, or throat); trouble breathing; wheezing; nausea; vomiting; severe stomach pain
  • Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint
  • Serious kidney problems: urinating less often than usual; swelling in your feet, ankles, or hands; unexplained weight gain
  • High blood potassium levels: nausea, muscle weakness, abnormal heartbeat
  • Severe allergic reaction: swelling of your lips, tongue, throat, or face; trouble breathing; rash

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Blurred vision

chest pain

confusion

diarrhea

difficult or labored breathing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

nausea

stomach pain

sweating

tightness in the chest

unusual tiredness or weakness

vomiting

Rare

Bleeding gums

cold, clammy skin

enlarged pupils

fast or slow heartbeat

increased sensitivity of the skin or eyes to sunlight

stiff or sore neck

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

Less common

Back pain

coughing

difficulty with moving

joint pain

muscle aching or cramping

muscle pains or stiffness

rash

swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Quinapril (Accupril)

thumbs-up

Pros

A first-choice medication for lowering blood pressure for many people

Available as a lower-cost generic

thumbs-down

Cons

Can't take during pregnancy

Might not work as well for lowering high blood pressure in Black adults

Hasn't been studied in children

pharmacist-tips

Pharmacist tips for Quinapril (Accupril)

pharmacist
  • Take quinapril (Accupril) with or without food at any time of day. If it's hurting your stomach, try taking it with food to help.

    • You might feel dizzy when you first start taking quinapril (Accupril) and when your dose is raised. This should get better as your body gets used to your new blood pressure. Lower your risk of falls by standing up slowly and carefully from a sitting or lying down position.

      • Drink plenty of fluids while you're taking quinapril (Accupril), especially on hot days or after exercising. Your blood pressure might drop too much if you don't have enough fluids in your body. This can worsen dizziness and raise your risk of falls. Ask your provider about how to safely stay hydrated if you have heart failure or kidney problems.

        • Check your blood pressure on a regular basis and keep a log of your readings. Bring your log to your office visits so you can discuss with your provider about how well quinapril (Accupril) is working for you.

          • Make sure to get any blood work done as you take quinapril (Accupril). These blood tests help your provider check for side effects like changes in your potassium levels and kidney health. Your dose might need to be changed based on your lab results.

            • Make sure to tell your providers about all the medications you're taking or planning to take. Quinapril (Accupril) can interact with other medications. This can affect how well your medications work or raise your risk for side effects. Your providers and pharmacists can check that your medications are safe for you to take together.

              • Continue to eat a variety of fruits and vegetables that you enjoy, follow a low-salt diet, and get regular exercise while you're taking quinapril (Accupril). This helps lower your blood pressure. You might be able to stop taking the medication if your blood pressure is well-controlled with these lifestyle changes.

                More on Quinapril (Accupril) tips

                faqs

                Frequently asked questions about Quinapril (Accupril)

                How long does it take for quinapril (Accupril) to work?
                Quinapril (Accupril) can start lowering your blood pressure within 1 hour, and it can take up to 4 hours for the medication's maximum effect. For any given dose, it can take 1 to 2 weeks to see noticeable changes in your blood pressure. That's why you'll take the medication at the prescribed dose for a few weeks before your provider considers any dose adjustments. Regularly check your blood pressure at home as instructed by your provider. Write down your blood pressure readings and bring them to your appointments. Your provider will discuss with you about how well quinapril (Accupril) is working for you based on your readings. It can take a little time and a few dose adjustments before your provider finds a dose that works best for you.
                Is quinapril (Accupril) the same as lisinopril?
                No, quinapril (Accupril) and lisinopril (Zestril) aren't the same. They're both ACE inhibitors, but they're different medications. First, both medications can treat high blood pressure and heart failure, but lisinopril (Zestril) can also help lower the risk of death after a heart attack. Second, quinapril (Accupril) hasn't been studied in children, but lisinopril (Zestril) can be used in children as young as 6 years old. Finally, lisinopril (Zesteril) is a longer-acting medication and is typically taken once per day, whereas quinapril (Accupril) is taken either once or twice per day. Talk with your provider if you have any questions about quinapril (Accupril) and lisinopril (Zestril).
                How long does quinapril (Accupril) stay in your system?
                Quinapril (Accupril) is a short-acting medication. It takes about 10 hours for most of quinapril (Accupril) to leave the body. This time frame is estimated based on the half-life of the medication. Keep in mind that how long the medication stays in your system can depend on your age and kidney function.
                Is quinapril (Accupril) a blood thinner?
                No, quinapril (Accupril) isn't a blood thinner; it doesn't prevent blood clots from forming and it doesn't raise your risk of bleeding. Instead, quinapril (Accupril) helps relax your blood vessels to lower your blood pressure.
                Is quinapril (Accupril) a beta blocker?
                No, quinapril (Accupril) isn't a beta blocker; it's an ACE inhibitor. Beta blockers and ACE inhibitors help lower blood pressure in different ways. ACE inhibitors, like quinapril (Accupril), are generally considered first-choice medications for blood pressure, but beta blockers aren't. In general, your provider might consider a beta blocker for you only if you can't take ACE inhibitors or if you have certain medical conditions. Your provider might prescribe a beta blocker along with quinapril (Accupril), depending on how well your blood pressure improves with quinapril (Accupril) by itself.
                Does quinapril (Accupril) cause weight gain?
                Weight gain isn't a known side effect of quinapril (Accupril). Talk to your provider if you notice unexplained changes in your weight during treatment.
                Does quinapril (Accupril) lower heart rate?
                Quinapril (Accupril) isn't known to lower heart rate. But some people have reported having small changes in heart rate while taking this medication. It isn't clear whether these changes in heart rate are caused by quinapril (Accupril). Ask your provider if you notice that your heart rate is lower than usual while you're taking quinapril (Accupril).
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                What are the risks and warnings for Quinapril (Accupril)?

                Quinapril (Accupril) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Not safe during pregnancy

                Quinapril (Accupril) can cause severe and sometimes life-threatening harm to unborn babies. For this reason, avoid using this medication during pregnancy. Before you start quinapril (Accupril), discuss with your provider about safer options to treat your blood pressure if you're pregnant or thinking of becoming pregnant. If you become pregnant while you're taking quinapril (Accupril), stop the medication and let your provider know right away.

                risk-warning

                Angioedema (swelling)

                • Risk factors: Black people | Having angioedema in the past

                  People who take ACE inhibitors, like quinapril (Accupril), can experience a rare, but serious side effect called angioedema. This involves swelling in different parts of the body, including the face, throat, and tongue. Swelling of the tongue or throat area can be potentially life-threatening since it can make it difficult to breathe. Angioedema can happen at any time during treatment. You might be more likely to experience angioedema if you're Black, an older adult, or of female sex. Get medical attention immediately if you notice any unusual swelling, stomach pain, or difficulty breathing. You'll have to stop taking quinapril (Accupril) if this happens.

                  risk-warning

                  Low blood pressure

                  • Risk factors: Not enough fluid in your body | Having diarrhea or vomiting for a long time | Low salt levels in your body | Taking higher doses of diuretic medications | Dialysis | Heart failure

                    Sometimes, taking quinapril (Accupril) can cause your blood pressure to drop too much. This can make you feel dizzy, tired, or lightheaded. This side effect is more common when you first start quinapril (Accupril) or when your provider raises your dose. Make sure to stay well-hydrated during treatment. Make sure to sit or lie down slowly while holding onto something if you feel dizzy, lightheaded, faint, or tired. And get medical help right away if you accidentally fall and hit your head.

                    risk-warning

                    Worsening kidney problems

                    • Risk factors: Severe heart failure | Kidney problems or renal artery stenosis | Not enough fluid in your body | Taking other medications that can cause kidney damage

                      Quinapril (Accupril) is usually good for the kidneys. But in some cases, it can make kidney problems worse. The risk is higher for people who have certain types of kidney problems, such as renal artery stenosis or kidney damage from severe heart failure. Your provider might order lab tests every so often to make sure your kidneys are healthy and working properly. You'll typically need these lab tests before you start quinapril (Accupril) and periodically during treatment as needed. Let your provider know if you're urinating less often than usual, as this could be a sign that your kidneys aren't working as well.

                      risk-warning

                      High potassium levels

                      • Risk factors: Diabetes | Kidney problems | Taking other medications that also raise potassium

                        Quinapril (Accupril) can raise the amount of potassium in your body, which can sometimes be dangerous. Your risk of developing high potassium is greater if you have diabetes or kidney problems or if you're taking other medications that also raise potassium levels. For this reason, make sure your provider knows your full medical history and what medications you're taking before starting treatment. Tell your healthcare provider right away if you experience signs of high potassium levels, such as nausea, muscle weakness, or abnormal heartbeat.

                        risk-warning

                        Liver problems

                        • Risk factors: History of liver problems | Drinking large amounts of alcohol

                          In some rare cases, people who took ACE inhibitors like quinapril (Accupril) developed a blocked bile duct. This condition can lead to liver problems or liver failure. Your provider might order blood tests to check your liver health from time to time. Let your provider know right away if you notice symptoms of liver problems, such as tiredness, stomach pain, or yellowing of your skin.

                          More on Quinapril (Accupril) warnings

                          dosage

                          Quinapril (Accupril) dosage forms

                          The average cost for 90 tablets of 40mg of Quinapril (Accupril) is $21.87 with a free GoodRx coupon. This is 90.43% off the average retail price of $228.43.
                          tablet
                          Tablet
                          DosageQuantityPrice as low asPrice per unit
                          5mg30 tablets$12.00$0.40
                          10mg30 tablets$15.42$0.51
                          20mg90 tablets$18.00$0.20
                          40mg90 tablets$21.87$0.24

                          Typical dosing for Quinapril (Accupril)

                          • High blood pressure: The typical starting dose is 10 mg or 20 mg by mouth once daily. For people taking a diuretic (water pill), the typical starting dose is 5 mg by mouth once daily. The usual dose ranges from 20 mg to 80 mg per day (as a single dose or split into two equal doses during the day).

                          • Heart failure: The typical starting dose is 5 mg by mouth twice daily. The usual dosage ranges from 10 mg to 20 mg by mouth twice daily.

                          Your provider will adjust your dose depending on your age, your kidney function, how well the medication is working to treat your condition, and whether you're having side effects.

                          More on Quinapril (Accupril) dosage forms

                          interactions

                          Interactions between Quinapril (Accupril) and other drugs

                          Quinapril (Accupril) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Quinapril (Accupril). Please note that only the generic name of each medication is listed below.

                          Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                          Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                          Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                          drug-cost

                          How much does Quinapril (Accupril) cost?

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                          contraindications-icon

                          Quinapril (Accupril) contraindications

                          Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Quinapril (Accupril) will not be safe for you to take.
                          alternatives

                          What are alternatives to Quinapril (Accupril)?

                          There are a number of medications that your doctor can prescribe in place of Quinapril (Accupril). Compare a few possible alternatives below.
                          Quinapril (Accupril)
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                          • High blood pressure

                          • Heart failure

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                          • High blood pressure

                          • Heart failure

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                          latest news

                          What is the latest news about Quinapril (Accupril)?

                          images

                          Quinapril (Accupril) images

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                          Red-Brown Oblong Apo And Qu-40 - Quinapril Hydrochloride 40mg Tablet
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                          This medicine is Brown, Round Tablet Imprinted With "Ce 123".Brown Round Ce 123 - Quinapril Hydrochloride 40mg Tablet
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                          This medicine is Brown, Oval Tablet Imprinted With "17" And "D".Brown Oval D And 17 - Quinapril Hydrochloride 40mg Tablet

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                          References

                          Best studies we found

                          Montford, J. R., et al. (2017). How dangerous is hyperkalemia? Journal of the American Society of Nephrology.

                          Parke-Davis Div of Pfizer Inc. (2023). Accupril- quinapril hydrochloride tablet, film coated [package insert]. DailyMed.

                          Rubenfire, M. (2018). 2017 guideline for high blood pressure in adults. American College of Cardiology.

                          GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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