The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Loss of appetite
- Vomiting
Less Common Side Effects
- Anemia (low red blood cell count)
- Getting sick often
- Bleeding more easily
- Changes or swelling to tongue
- Blood in urine
- Changes to heart rhythm
Pyrimethamine serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction
Source: DailyMed
The following Pyrimethamine side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Black, tarry stools
bleeding gums
blistering, peeling, or loosening of the skin
blood in the urine or stools
chills
difficulty swallowing
dizziness
fainting spells
fast or irregular heartbeat
irritation or soreness of the tongue
joint or muscle pain
lower back or side pain
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
painful or difficult urination
pale skin
pinpoint red spots on the skin
red, irritated eyes
red skin lesions, often with a purple center
sores, ulcers, or white spots on the lips or in the mouth
swollen glands
tightness in the chest
unusual bleeding or bruising
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


